Anti-Mouse CD105 (Endoglin) PE

Also known as: Endoglin, ENG

Clone: MJ7/18

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 12-1051

Cat. No. Size
12-1051-81 50 ug
12-1051-82 100 ug
12-1051-83 200 ug
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Data for Anti-Mouse CD105 (Endoglin) PE.

Staining of bEnd.3 cell line with 0.25 ug of Rat IgG2a kappa Isotype Control PE (cat. 12-4321) (open...View More

  • Data for Anti-Mouse CD105 (Endoglin) PE.
Description

Description: The MJ7/18 monoclonal antibody reacts with the mouse CD105 molecule, also known as Endoglin. This 90 kDa disulfide-linked homodimer is expressed by vascular endothelial cells. It is suggested that CD105 functions in adhesion and embryonic angiogenesis.

Details
Host Rat
Isotype IgG2a, kappa
Reactivity Mouse
Conjugate PE
Laser Blue Laser, Green Laser, Yellow-Green Laser
Emit 575 nm
Excite 488 - 561 nm
Reported Applications Flow Cytometric Analysis
Documentation
TDS Link Download TDS
Additional Formats
Cat. No. Name Excite Emit Application Reg.
13-1051 Anti-Mouse CD105 (Endoglin) Biotin FC RUO
48-1051 Anti-Mouse CD105 (Endoglin) eFluor® 450 405 nm 450 nm FC RUO
14-1051 Anti-Mouse CD105 (Endoglin) Purified FC, IHC, IP, WB RUO
Related Products
Cat. No. Name Excite Emit Application Reg.
12-1057 Anti-Human CD105 (Endoglin) PE 488 - 561 nm FC RUO
12-4321 Rat IgG2a K Isotype Control PE 488 - 561 nm FC RUO
14-1057 Anti-Human CD105 (Endoglin) Purified FC RUO
16-1057 Anti-Human CD105 (Endoglin) Functional Grade Purified FA RUO
17-1057 Anti-Human CD105 (Endoglin) APC 633 - 647 nm 660 nm FC RUO
References

References: Ge, A. Z. and E. C. Butcher. 1994. Cloning and expression of a cDNA encoding mouse endoglin, an endothelial cell TGF-beta ligand. Gene 138(1-2): 201-6.

Tokita D, Ohdan H, Onoe T, Hara H, Tanaka Y, Asahara T. Liver sinusoidal endothelial cells contribute to alloreactive T-cell tolerance induced by portal venous injection of donor splenocytes.Transpl Int. 2005 Feb;18(2):237-45.

Quintanilla M, Ramirez JR, et al. 2003. Expression of the TGF-beta coreceptor endoglin in epidermal keratinocytes and its dual role in multistage mouse skin carcinogenesis. Oncogene. 22(38):5976-85. (MJ7/18, IHC formalin-fixed and WB, PubMed)

Onoe T, Ohdan H, et al. 2005. Liver sinusoidal endothelial cells tolerize T cells across MHC barriers in mice. J Immunol. 175(1):139-46. (MJ7/18, IHC frozen, PubMed)

Korpanty G, Carbon JG, et al. 2007. Monitoring response to anticancer therapy by targeting microbubbles to tumor vasculature. Clin Cancer Res. 13(1):323-30. (MJ7/18, IHC frozen, PubMed)

Perez-Gomez E, Villa-Morales M, et al. 2007. A role for endoglin as a suppressor of malignancy during mouse skin carcinogenesis. Cancer Res. 67(21):10268-77. (MJ7/18, WB, PubMed)