Anti-Mouse CCL5 (RANTES) Purified

Also known as: CCL-5, regulated upon activation normal T-cell expressed, and presumably secreted, SIS-delta, SCYA5

Clone: R6G9

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 14-7085

Cat. No.	Size
14-7085-80	25 ug
14-7085-82	100 ug
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Immunoblot with Anti-Mouse CCL5 (RANTES) Purified. Raw 264.7 cells were treated with Brefeldin A...View More

Description

Description: RANTES (Regulated on Activation, Normal T Expressed and Secreted) is an 8kD member of the C-C family of chemkines (CCL5). It is a proinflammatory chemoattractant for several cell types including CD4+ T cells, monocytes and eosinophils. In contrast to other members of the chemokine superfamily, RANTES has been observed to be downregulated upon activation in T cells. In other secreting cells, upregulation is observed in response to activation.

Details

Host	Mouse
Isotype	IgG1
Reactivity	Mouse
Conjugate	Purified
Reported Applications	Western Blotting

Documentation

TDS Link	Download TDS

Related Products

Cat. No.	Name	Excite	Emit	Application	Reg.
14-4714	Mouse IgG1 K Isotype Control Purified			FC, ICC, IHC, IP, WB	RUO
14-7993	Anti-Mouse/Rat CCL5 (RANTES) Purified (To be Discontinued; refer to monoclonal Cat. No. 14-7085)			WB	RUO

References

References: Schall TJ. Biology of the RANTES/SIS cytokine family.Cytokine. 1991 May;3(3):165-83.

Danoff TM, Lalley PA, Chang YS, Heeger PS, Neilson EG. Cloning, genomic organization, and chromosomal localization of the Scya5 gene encoding the murine chemokine RANTES. J Immunol. 1994 Feb 1;152(3):1182-9.

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Antigens	Area of Biology	Cell Type	Formats
CCL5 (RANTES)	Cytokines, Chemokines, Growth Factors	Macrophage & Monocyte Cells	Purified