Anti-Mouse Allergin-1 eFluor® 660

Also known as: allergy inhibitory receptor 1, Mast cell antigen 32

Clone: TX83

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 50-5926

Cat. No.	Size
50-5926-80	25 ug
50-5926-82	100 ug
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Staining of mouse splenocytes with Anti-Mouse CD11b FITC (cat. 11-0112), Anti-Mouse CD11c PE (cat....View More

Description

Description: The TX83 monoclonal antibody reacts with mouse allergin-1, a 60-kDa inhibitory immunoglobulin-like receptor. In mice, allergin-1 is expressed preferentially on mast cells, but can also be found on dendritic cells, macrophages, and neutrophils. When allergin-1 is co-ligated with FceRI, it inhibits FceRI-mediated degranulation of mast cells, which inhibits immediate hypersensitvity reactions. There is currently no ligand identified for this receptor.

Details

Host	Mouse
Isotype	IgG1, kappa
Reactivity	Mouse
Conjugate	eFluor 660
Laser	Red Laser
Emit	668 nm
Excite	633 - 647 nm
Reported Applications	Flow Cytometric Analysis

Documentation

TDS Link	Download TDS

Related Products

Cat. No.	Name	Excite	Emit	Application	Reg.
11-0112	Anti-Mouse CD11b FITC	488 nm	518 nm	FC	RUO
12-0114	Anti-Mouse CD11c PE	488 - 561 nm		FC	RUO
50-4714	Mouse IgG1 K Isotype Control eFluor® 660 (Alexa Fluor® 647 Replacement)	633 - 647 nm	668 nm	FC, IHC	RUO

References

References: Hitomi K, Tahara-Hanaoka S, Someya S, Fujiki A, Tada H, Sugiyama T, Shibayama S, Shibuya K, Shibuya A. An immunoglobulin-like receptor, Allergin-1, inhibits immunoglobulin E-mediated immediate hypersensitivity reactions. Nat Immunol. 2010 Jul;11(7):601-7. (TX83, FC, PubMed)

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Antigens	Area of Biology	Formats
Allergin-1	Innate Immunity	eFluor 660