Stem Cell Biology Overview
eBioscience: The Source for Complete Stem Cell Analysis
The field of stem cell biology was borne from the identification of hematopoietic stem cells (HSC) in 1961 by Till and McCullough. In a landmark experiment they demonstrated that clonally-marked mouse bone marrow cells had the potential to give rise to a spleen colony-forming unit (CFU-S) and that all of the cells composing the CFU-S were derived from a single clone. It is now known that HSCs progress through defined stages of maturation that result in a gradual loss of multi-lineage potential, and commitment to various blood cell phenotypes. From these early beginnings the principles of stem cell biology have been applied to explain the formation of countless other tissues.
In recent years, ground-breaking discoveries and advancements have sparked renewed interest and excitement in the field of stem cell biology. eBioscience is pleased to provide an offering of reagents supporting all aspects of stem cell research including their culture, isolation and characterization. eBioscience provides a diverse breadth of fluorochrome-conjugated antibodies for the identification of stem cells. With the introduction of the eFluor® brand of fluorochromes, we now offer the most robust panel of fluorochromes for multicolor applications. Furthermore, eBioscience offers a variety of reagents to analyze aspects of cell biology and function including cell proliferation, viability, calcium-flux and apoptosis. As a leading provider of stem cell reagents, eBioscience is committed to adding to, and adapting, our portfolio in response to new findings in the field of stem cell biology.