Anti-Human CD120a (TNF-RI)

Description: The monoclonal antibody H398 recognizes the extracellular part of the Tumor Necrosis Factor Receptor type I (TNF-RI) of the membrane-bound as well as the soluble receptor.
The monoclonal antibody H398 can be used for immuno assay, flow cytometry, immuno precipitation and Western blotting. Furthermore, the monoclonal antibody H398 is useful for immunohistology on frozen sections. The monoclonal antibody H398 is also useful as antagonistic antibody in functional studies. Be aware that the antibody competes with TNF-alpha.

Citations: Rosenthal,Dean S.; Velena,Alfredo; Chou,Feng Pai; Schlegel,Richard; Ray,Radharaman; Benton,Betty; Anderson,Dana; Smith,William J.; Simbulan-Rosenthal,Cynthia M.. Expression of Dominant-negative Fas-associated Death Domain Blocks Human Keratinocyte Apoptosis and Vesication Induced by Sulfur Mustard. Journal of Biological Chemistry 2003;278:8531-8540. (Link)

Lama,Juan; Ware,Carl F.. Human Immunodeficiency Virus Type 1 Nef Mediates Sustained Membrane Expression of Tumor Necrosis Factor and the Related Cytokine LIGHT on Activated T Cells. Journal of Virology 2000;74:9396-9402. (Link)

Choi,Kyung Bok; Wong,Fred; Harlan,John M.; Chaudhary,Preet M.; Hood,Leroy; Karsan,Aly. Lipopolysaccharide Mediates Endothelial Apoptosis by a FADD-dependent Pathway. Journal of Biological Chemistry 1998;273:20185-20188. (Link)

Geilen,Christoph C.; Bektas,Meryem; Wieder,Thomas; Kodelja,Vitam; Goerdt,Sergji; Orfanos,Constantin E.. 1alpha ,25-Dihydroxyvitamin D3 Induces Sphingomyelin Hydrolysis in HaCaT Cells via Tumor Necrosis Factor alpha. Journal of Biological Chemistry 1997;272:8997-9001. (Link)

Kugler,Wilfried; Erdlenbruch,Bernhard; Junemann,Anja; Heinemann,Dagmar; Eibl,Hansjorg; Lakomek,Max. Erucylphosphocholine-induced apoptosis in glioma cells: involvement of death receptor signalling and caspase activation. Journal of Neurochemistry 2002;82:1160-1170. (Link)

Tang,Damu; Lahti,Jill M.; Grenet,Jose; Kidd,Vincent J.. Cycloheximide-induced T-cell Death Is Mediated by a Fas-associated Death Domain-dependent Mechanism. Journal of Biological Chemistry 1999;274:7245-7252. (Link)

Harashima,Shin ichi; Horiuchi,Takahiko; Hatta,Nobuaki; Morita,Chika; Higuchi,Masanori; Sawabe,Takuya; Tsukamoto,Hiroshi; Tahira,Tomoko; Hayashi,Kenshi; Fujita,Shigeru; Niho,Yoshiyuki. Outside-to-Inside Signal Through the Membrane TNF-{{alpha}} Induces E-Selectin (CD62E) Expression on Activated Human CD4+ T Cells. The Journal of Immunology 2001;166:130-136. (Link)

Chen,B.; Tong,Z.; Ye,Q.; Nakamura,S.; Costabel,U.; Guzman,J.. Expression of tumour necrosis factor receptors by bronchoalveolar cells in hypersensitivity pneumonitis. European Respiratory Journal 2005;25:1039-1043. (Link)