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Anti-Human TNF alpha Alexa Fluor® 647 (Discontinued. Refer to Alternative Format APC cat. 17-7349)

Also known as: Tumor Necrosis Factor alpha, TNFa TNF-a, TNF-alpha

Clone: MAb11

RUO: For Research Use Only. Not for use in diagnostic procedures.

Attention: Discontinued. Refer to Replacement Format APC cat. 17-7349

SKU# 51-7349

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Data for Anti-Human TNF alpha Alexa Fluor® 647 (To Be Discontinued. Refer to Alternative Format: APC cat. 17-7349).

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  • Data for Anti-Human TNF alpha Alexa Fluor® 647 (To Be Discontinued. Refer to Alternative Format: APC cat. 17-7349).
Description

Description: The MAb11 antibody reacts with human tumor necrosis factor-alpha (TNF-α ), a 17 kDa cytokine produced by monocytes, macrophages, neutrophils, NK cells and CD4+ T cells. TNF-α has cytolytic activity against a range of tumor cells and is important in immune regulation. TNF-α forms dimers and trimers and also exists as a 26 kDa membrane bound form. The MAb11 antibody is a neutralizing antibody.

Details
Host Mouse
Isotype IgG1, kappa
Reactivity Human
Conjugate Alexa Fluor 647
Laser Red Laser
Emit 668 nm
Excite 633 nm
Legal Alexa Fluor® and Pacific Blue® are registered trademarks of and licensed under patents assigned to Molecular Probes, Inc. for research use only. This product is subject to an agreement between Molecular Probes, Inc. and eBioscience, and the manufacture, use, sale or import of this product may be subject to one or more U.S. patents, pending applications and corresponding foreign equivalents, owned by Molecular Probes, Inc. (a wholly owned subsidiary of Invitrogen Corp). The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product for life science research or as an ASR. The buyer cannot use this product for manufacturing or for any other screening (specifically including use in combination with microarrays or High Content Screening) or testing purpose, other than as an ASR. For information on purchasing a license to this product for purposes other than life science research or use as an ASR, contact Molecular Probes, Inc.
Reported Applications Intracellular Staining Followed by Flow Cytometric Analysis
Documentation

For complete product information, please download the TDS or IFU document.

TDS Link Download TDS
Additional Formats
Cat. No. Name Excite Emit Application Reg.
12-7349 Anti-Human TNF alpha PE 488 nm 575 nm FC RUO
14-7349 Anti-Human TNF alpha Purified FC RUO
11-7349 Anti-Human TNF alpha FITC 488 nm 518 nm FC RUO
13-7349 Anti-Human TNF alpha Biotin ELISA RUO
25-7349 Anti-Human TNF alpha PE-Cy7 488 nm 760 nm FC RUO
45-7349 Anti-Human TNF alpha PerCP-Cy5.5 488 nm 690 nm FC RUO
53-7349 Anti-Human TNF alpha Alexa Fluor® 488 488 nm 519 nm FC RUO
17-7349 Anti-Human TNF alpha APC 633 nm 660 nm FC RUO
48-7349 Anti-Human TNF alpha eFluor® 450 405 nm 450 nm FC RUO
56-7349 Anti-Human TNF alpha Alexa Fluor® 700 633 nm 723 nm FC RUO
References

References:
Danis, V. A., G. M. Franic, et al. (1991). "Effects of granulocyte-macrophage colony-stimulating factor (GM-CSF), IL-2, interferon-gamma (IFN-gamma), tumor necrosis factor-alpha (TNF-alpha) and IL-6 on the production of immunoreactive IL-1 and TNF-alpha by human monocytes." Clin Exp Immunol 85(1): 143-50.
Rathjen, D. A., K. Cowan, et al. (1991). "Antigenic structure of human tumour necrosis factor: recognition of distinct regions of TNF alpha by different tumour cell receptors." Mol Immunol 28(1-2): 79-86.

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