Human TGF-beta 1 Instant ELISA

Also known as: Camurati-Engelmann disease, DPD1

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# BMS249/3INST*

Cat. No.	Size
BMS249/3INST	128 tests
BMS249/3INSTTEN	10 x 128 tests
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Description

Description: The human TGF-beta1 Instant ELISA is an enzyme-linked immunosorbent assay for the quantitative detection of human TGF-beta1. The human TGF-beta1 Instant ELISA is for research use only. Not for diagnostic or therapeutic procedures.

TGF-beta plays a critical role in cellular growth, development, differentiation, proliferation, extracellular matrix (ECM) synthesis and degradation, control of mesenchymal-epithelial interactions during embryogenesis, immune modulation, apoptosis, cell cycle progression, angiogenesis, adhesion and migration and leukocyte chemotaxis. It has both tumor suppressive and tumor promoting activities and is highly regulated at all levels. TGF-beta1 is the key mediator in the pathophysiology of tissue repair and human fibrogenesis: balance between production and degradation of type I collagen, and fibrosis and scarring in organ and tissue. TGF-beta1 promotes Treg cell differentiation resulting in IL-10/TGF-beta1 production and Th1 cell and Th2 cell suppression.

Details

Reactivity	Human
Sample Volume	40 uL (pretreated)
Suitable Sample Types	serum, plasma (EDTA, citrate, heparin), cell culture supernatant
Sensitivity	17.12 pg/ml
Standard Curve Range	31 - 2000 pg/ml
Components	Aluminium pouch(es) with a Microwell Plate coated with monoclonal antibody to human TGF-beta1, Biotin-Conjugate (anti-human TGF-beta1 polyclonal antibody), Streptavidin-HRP and Sample Diluent, lyophilized Aluminium pouch(es) with a human TGF-b1 Standard curve (coloured) Assay Buffer Concentrate 20x (PBS with 1% Tween 20 and 10% BSA) Wash Buffer Concentrate 20x (phosphate-buffered saline with 1% Tween 20) 1N HCl (pretreatment of samples) 1N NaOH (pretreatment of samples) Sample Diluent Substrate Solution (tetramethyl-benzidine) Stop Solution (1M Phosphoric acid) Adhesive Films
Reported Applications	ELISA

Documentation

TDS Link	Download TDS

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References

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