Anti-Human Synaptophysin Alexa Fluor® 647 (To Be Discontinued. Refer to Cat. No 50-6525)

Also known as: Major Synaptic Vesicle Protein p38

Clone: EP10

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 51-6525

Cat. No.	Size
51-6525-80	25 ug
51-6525-82	100 ug
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Immunohistochemistry of formalin-fixed paraffin embedded human cerebellum using 10 ug/mL of Mouse...View More

Description

Description: This EP10 monoclonal antibody reacts with human Synaptophysin, which is also known as Major Synaptic Vesicle Protein p38. This 38-kDa integral membrane protein is expressed on neuronal presynaptic vesicles in the brain, spinal cord, retina, neuromuscular junctions, and adrenal medulla. Synaptophysin is also expressed in neuroendocrine tumors and neuroblastomas. Synaptophysin has been reported to play a role in synaptic vesicle trafficking.

Details

Host	Mouse
Isotype	IgG1
Reactivity	Armenian Hamster, Golden Syrian Hamster, Human
Conjugate	Alexa Fluor 647
Laser	Red Laser
Emit	668 nm
Excite	633 - 647 nm
Legal	Alexa Fluor® and Pacific Blue® are registered trademarks of and licensed under patents assigned to Molecular Probes, Inc. for research use only. This product is subject to an agreement between Molecular Probes, Inc. and eBioscience, and the manufacture, use, sale or import of this product may be subject to one or more U.S. patents, pending applications and corresponding foreign equivalents, owned by Molecular Probes, Inc. (a wholly owned subsidiary of Invitrogen Corp). The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product for life science research or as an ASR. The buyer cannot use this product for manufacturing or for any other screening (specifically including use in combination with microarrays or High Content Screening) or testing purpose, other than as an ASR. For information on purchasing a license to this product for purposes other than life science research or use as an ASR, contact Molecular Probes, Inc.
Reported Applications	Immunohistochemical Staining of Formalin-Fixed Paraffin Embedded Tissue Sections, Immunocytochemistry

Documentation

TDS Link	Download TDS

Additional Formats

Cat. No.	Name	Excite	Emit	Application	Reg.
14-6525	Anti-Human Synaptophysin Purified			ICC, IHC, IP, WB	RUO
50-6525	Anti-Human Synaptophysin eFluor® 660 (Alexa Fluor® 647 Replacement)	633 - 647 nm	668 nm	ICC, IHC	RUO
42-6525	Anti-Human Synaptophysin eFluor® 615	595 nm	615 nm	ICC, IHC	RUO

Related Products

Cat. No.	Name	Excite	Emit	Application	Reg.
51-4714	Mouse IgG1 K Isotype Control Alexa Fluor® 647 (Discontined. Refer to Cat. No. 50-4714)	633 - 647 nm	668 nm	FC, ICC, IHC	RUO

References

References: Arthur CP, Stowell MH. Structure of synaptophysin: a hexameric MARVEL-domain channel protein. Structure. 2007 Jun;15(6):707-14.

Honer WG, Kaufmann CA, Davies P. Characterization of a synaptic antigen of interest in neuropsychiatric illness. Biol Psychiatry. 1992 Jan 15;31(2):147-58. (EP10, ICC)

Südhof TC, Lottspeich F, Greengard P, Mehl E, Jahn R. A synaptic vesicle protein with a novel cytoplasmic domain and four transmembrane regions. Science. 1987 Nov 20;238(4830):1142-4.

Wiedenmann B, Franke WW. Identification and localization of synaptophysin, an integral membrane glycoprotein of Mr 38,000 characteristic of presynaptic vesicles. Cell. 1985 Jul;41(3):1017-28.

View More Products

Antigens	Area of Biology	Formats
Synaptophysin	Angiogenesis	Alexa Fluor 647