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SKU# 12-9994
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Staining of normal human peripheral blood cells with Anti-Human CD8 APC-eFluor® 780 (cat. 47-0088)...View More
Description: The dG9 antibody clone reacts with human perforin (pore-forming protein, pfp). Perforin is one of the cytolytic mediators present in the cytoplasmic granules of cytotoxic T lymphocytes (CTL) and natural killer cells (NK). Perforin is involved in the killing function by CTLs and NKs and has an important role in the immune response against tumors and virus infections.
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References: M.J. Smyth, et al, (1990) J Exp Med 171: 1269-1281.A. Hameed, et al, (1992) Am J Pathol 140: 1025-1030.P.L. Jose, et al, (1994) J Immunol 148: 3354-3360.B.C. Schlesinger & L. Cheng, (1994) Immunol 81: 291-295.C.C. Liu, et al, (1995) Immunol Today 16: 194-201.
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