Anti-Human/Non-Human Primate CD45RA PerCP-eFluor® 710

Description: This GRT22 monoclonal antibody reacts with human and non-human primate CD45RA, a 220 kDa molecule expressed by subpopulations of CD4+ and CD8+ naïve peripheral T lymphocytes and B cells.

The GRT22 antibody crossreacts to rhesus CD45RA. Crossblocking studies indicate that GRT22 and HI100 recognize different epitopes.

References: Matutes E, Brito-Babapulle V, Swansbury J, Ellis J, Morilla R, Dearden C, Sempere A, Catovsky D. Clinical and laboratory features of 78 cases of T-prolymphocytic leukemia. Blood. 1991 Dec 15;78(12):3269-74. (GRT22, ICC)

Worner I, Matutes E, Beverley PC, Catovsky D. The distribution of CD45R, CD29 and CD45RO (UCHL1) antigens in mature CD4 positive T-cell leukaemias. Br J Haematol. 1990 Apr;74(4):439-44. (GRT22)

Ruiz-Cabello F, Huelin C, Pedrinaci S, Lopez Nevot MA, Garrido F. Different CD45 and CD45R epitopes involved in T cell proliferation and NK cytotoxicity. Hybridoma. 1989 Feb;8(1):1-11. (GRT22)

Knapp, W., B. Dorken, et al. Leucocyte Typing IV: White Cell Differentiation Antigens. 1989. Oxford University Press. New York.