Anti-Human Nanog Purified

Also known as: Homeobox protein NANOG, ES cell-associated protein 4, Early embryo specific expression NK-type homeobox protein, Homeobox transcription factor Nanog

Clone: hNanog.2

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 14-5768

Cat. No.	Size
14-5768-80	25 ug
14-5768-82	100 ug

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Description

Description: The hNanog.2 antibody was generated against and reacts with human Nanog, a homeobox transcription factor. In addition to the known Oct4 and Stat3 transcriptional operating systems, Nanog plays a crucial role in the second embryonic cell fate specification following formation of the blastocyst. Nanog was identified as a gene specifically expressed in mouse ES cells and preimplantation embryos and is capable of maintaining ES cell self-renewal independently of LIF/Stat3. Potential cross-reactivity of this antibody to other proteins has not been determined.

Details

Host	Mouse
Isotype	IgG1, kappa
Reactivity	Human
Conjugate	Purified
Reported Applications	Western Blotting

Documentation

For complete product information, please download the TDS or IFU document.

TDS Link	Download TDS

Additional Formats

References

References: Mitsui K, Tokuzawa Y, Itoh H, Segawa K, Murakami M, Takahashi K, Maruyama M, Maeda M, Yamanaka S. 2003. The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell. 113(5):631-42.
Cavaleri F, Scholer HR. 2003. Nanog: a new recruit to the embryonic stem cell orchestra. Cell. 113(5):551-2

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Antigens	Area of Biology	Cell Type	Formats
Nanog	Stem Cell Biology Transcription Factors	Embryonic Stem Cells	Purified