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SKU# 14-5768
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NTERA cell line lysate was loaded at 1x10e5 cells/lane, probed with 1 ug/mL of Anti-Human Nanog...View More
Description: The hNanog.2 antibody was generated against and reacts with human Nanog, a homeobox transcription factor. In addition to the known Oct4 and Stat3 transcriptional operating systems, Nanog plays a crucial role in the second embryonic cell fate specification following formation of the blastocyst. Nanog was identified as a gene specifically expressed in mouse ES cells and preimplantation embryos and is capable of maintaining ES cell self-renewal independently of LIF/Stat3. Potential cross-reactivity of this antibody to other proteins has not been determined.
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References: Mitsui K, Tokuzawa Y, Itoh H, Segawa K, Murakami M, Takahashi K, Maruyama M, Maeda M, Yamanaka S. 2003. The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell. 113(5):631-42.Cavaleri F, Scholer HR. 2003. Nanog: a new recruit to the embryonic stem cell orchestra. Cell. 113(5):551-2
Anti-Mouse Nanog Purified
Anti-Mouse RAE1 delta Purified
Anti-Mouse OVA257-264 (SIINFEKL) peptide bound to H-2Kb Purified
Anti-Mouse Ea52-68 peptide bound to I-Ab Purified
Anti-Mouse gamma delta TCR Purified
