Anti-CD27 Purified

Also known as: TNFRSF7

Clone: LG.7F9

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 14-0271

Cat. No.	Size
14-0271-82	100 ug
14-0271-85	500 ug
Please inquire about custom configurations or bulk packaging.

To enable ordering, please select your country. Cookies will need to be enabled to continue on our website. View our Privacy Policy.

Staining of mouse splenocytes with 0.25 ug Hamster IgG Isotype Control Purified (cat. 14-4888) (open...View More

Description

Description: The LG.7F9 monoclonal antibody reacts with mouse CD27, a lymphocyte-specific member of the TNFR superfamily. CD27 is expressed by virtually all mature T cells and by a subpopulation of B cells, mainly memory B cells. In mouse, CD27 has been found on nearly all thymocytes excluding a population of CD46-CD8- precursors. CD27 binds to CD70 and, through this interaction, plays an important role in T cell-B cell interaction. It has been reported that triggering CD27 plays an important role in the maturation of CD4+ and CD8+ effector cells. LG.7F9 cross-reacts with human and rat CD27.

Details

Host	Armenian Hamster
Isotype	IgG
Reactivity	Human, Mouse, Rat
Conjugate	Purified
Reported Applications	Flow Cytometric Analysis, Functional Assays, Immunoprecipitation

Documentation

TDS Link	Download TDS

Additional Formats

Cat. No.	Name	Excite	Emit	Application	Reg.
17-0271	Anti-CD27 APC	633 - 647 nm	660 nm	FC	RUO
13-0271	Anti-CD27 Biotin			FC	RUO
11-0271	Anti-CD27 FITC	488 nm	518 nm	FC	RUO
46-0271	Anti-CD27 PerCP-eFluor® 710	488 nm	710 nm	FC	RUO
25-0271	Anti-CD27 PE-Cyanine7	488 - 561 nm	775 nm	FC	RUO
47-0271	Anti-CD27 APC-eFluor® 780	633 - 647 nm	780 nm	FC	RUO
16-0271	Anti-CD27 Functional Grade Purified			FC, FA	RUO
12-0271	Anti-CD27 PE	488 - 561 nm	575 nm	FC	RUO

Related Products

Cat. No.	Name	Excite	Emit	Application	Reg.
11-4111	Anti-Armenian Hamster IgG FITC	488 nm		FC	RUO
14-4888	Armenian Hamster IgG Isotype Control Purified			FC, ICC, IHC	RUO

References

References: Gravestein LA, Nieland JD, Kruisbeek AM, Borst J. 1995. Novel mAbs reveal potent co-stimulatory activity of murine CD27. International Immunology 7(4): 551-557

Tesselaar K, Gravenstine LA, et al. 1997. Characterization of Murine CD70, the Ligand of the TNF Receptor Family Member CD27. The Journal of Immunology 159: 4959-4965

Tesselaar K, Xiao Y, et al. 2002. Expression of the Murine CD27 Ligand CD70 in Vitro and In Vivo. The Journal of Immunology 170: 33-40

View More Products

Antigens	Area of Biology	Cell Type	Formats
CD27	Adaptive Immunity Apoptosis	B Cells NK & NKT Cells T Cells	Purified