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Anti-CD27 Biotin

Also known as: TNFRSF7

Clone: LG.7F9

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 13-0271

Cat. No. Size
13-0271-81 50 ug
13-0271-82 100 ug
13-0271-85 500 ug
Please inquire about custom configurations or bulk packaging.

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Data for Anti-CD27 Biotin.

Staining of C57BL/6 splenocytes with Anti-Human/Mouse CD45R (B220) APC (cat. 17-0452) and 0.06 ug of...View More

  • Data for Anti-CD27 Biotin.
Description

Description: The LG.7F9 monoclonal antibody reacts with mouse CD27, a lymphocyte-specific member of the TNFR superfamily. CD27 is expressed by virtually all mature T cells and by a subpopulation of B cells, mainly memory B cells. In mouse, CD27 has been found on nearly all thymocytes excluding a population of CD46-CD8- precursors. CD27 binds to CD70 and, through this interaction, plays an important role in T cell-B cell interaction. It has been reported that triggering CD27 plays an important role in the maturation of CD4+ and CD8+ effector cells. LG.7F9 cross-reacts with human and rat CD27.

Details
Host Armenian Hamster
Isotype IgG
Reactivity Human, Mouse, Rat
Conjugate Biotin
Reported Applications Flow Cytometric Analysis
Documentation

For complete product information, please download the TDS or IFU document.

TDS Link Download TDS
Additional Formats
Cat. No. Name Excite Emit Application Reg.
16-0271 Anti-CD27 Functional Grade Purified FC, FA RUO
25-0271 Anti-CD27 PE-Cy7 488 - 561 nm 760 nm FC RUO
46-0271 Anti-CD27 PerCP-eFluor® 710 488 nm 710 nm FC RUO
11-0271 Anti-CD27 FITC 488 nm 518 nm FC RUO
12-0271 Anti-CD27 PE 488 - 561 nm 575 nm FC RUO
17-0271 Anti-CD27 APC 633 - 647 nm 660 nm FC RUO
47-0271 Anti-CD27 APC-eFluor® 780 633 nm 780 nm FC RUO
14-0271 Anti-CD27 Purified FC, FA, IP RUO
References

References: Gravestein LA, Nieland JD, Kruisbeek AM, Borst J. 1995. Novel mAbs reveal potent co-stimulatory activity of murine CD27. International Immunology 7(4): 551-557

Tesselaar K, Gravenstine LA, et al. 1997. Characterization of Murine CD70, the Ligand of the TNF Receptor Family Member CD27. The Journal of Immunology 159: 4959-4965

Tesselaar K, Xiao Y, et al. 2002. Expression of the Murine CD27 Ligand CD70 in Vitro and In Vivo. The Journal of Immunology 170: 33-40

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