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Description: The 2H12 antibody reacts with the human, mouse and rat Bcl-xL molecule, an approximately 27 kDa oncoprotein. Bcl-xL functions as a central repressor of several apoptotic signals.
References: Hsu YT, et. al. Proceedings of the National Academy of Sciences of the United States of America, 1997, 94(8):3668-72. Hsu YT, et. al. Journal of Biological Chemistry, 1997, 272(21):13829-34.