Anti-Human CD18 (LFA-1beta) Purified

Description: BMS103 is also suitable as primary antibody in staining for FACS analysis, BMS103FI can be used for direct staining of cells, BMS103BT can be used in a 2-step procedure using the biotin-(strept)avidin system.
BMS103 can be used as a neutralizing agent.

Recommended CD18 is a 90-95 kDa type I transmembrane protein that heterodimerizes with the a chain of CD11a, CD11b and CD11c. The CD18/CD11a complex is also known as lymphocyte function-associated antigen-1 (LFA-1) and plays an important role in cellular adhesion and inflammatory reactions. CD18 is expressed broadly by human lymphocytes and monocytes. Peripheral blood granulocytes also express CD18, but at lower levels.

Citations: Rajasagi,Mohini; Vitacolonna,Mario; Benjak,Bojan; Marhaba,Rachid; Zoller,Margot. CD44 promotes progenitor homing into the thymus and T cell maturation. Journal of Leukocyte Biology 2009;85:251-261. (Link)

Agrewala; Kumar; Vohra. Potential role of B7-1 and CD28 molecules in immunosuppression in leprosy. Clinical and Experimental Immunology 1998;111:56-63. (Link)

Mena,Mari Pau; Sacanella,Emilio; Vazquez-Agell,Monica; Morales,Mercedes; Fito,Montserrat; Escoda,Rosa; Serrano-Martinez,Manuel; Salas-Salvado,Jordi; Benages,Neus; Casas,Rosa; Lamuela-Raventos,Rosa M.; Masanes,Ferran; Ros,Emilio; Estruch,Ramon. Inhibition of circulating immune cell activation: a molecular antiinflammatory effect of the Mediterranean diet. American Journal of Clinical Nutrition 2009;89:248-256. (Link)