Anti-Human CD18 (LFA-1beta) Biotin

Also known as: Leukocyte function-associated antigen 1 beta

Clone: R3.3

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# BMS103BT*

Cat. No. Size
BMS103BT 100 tests
Please inquire about custom configurations or bulk packaging.

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Description

Description: BMS103 is also suitable as primary antibody in staining for FACS analysis, BMS103FI can be used for direct staining of cells, BMS103BT can be used in a 2-step procedure using the biotin-(strept)avidin system.
BMS103 can be used as a neutralizing agent.

Recommended CD18 is a 90-95 kDa type I transmembrane protein that heterodimerizes with the a chain of CD11a, CD11b and CD11c. The CD18/CD11a complex is also known as lymphocyte function-associated antigen-1 (LFA-1) and plays an important role in cellular adhesion and inflammatory reactions. CD18 is expressed broadly by human lymphocytes and monocytes. Peripheral blood granulocytes also express CD18, but at lower levels.

Details
Host Mouse
Isotype lgG1
Reactivity Human
Conjugate Biotin
Reported Applications Flow Cytometric Analysis
Documentation
TDS Link Download TDS
Additional Formats
Cat. No. Name Excite Emit Application Reg.
BMS103* Anti-Human CD18 (LFA-1beta) Purified FC, IHC, FA RUO
BMS103FI* Anti-Human CD18 (LFA-1beta) FITC 488 nm 518 nm FC RUO
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References

Citations: Rajasagi,Mohini; Vitacolonna,Mario; Benjak,Bojan; Marhaba,Rachid; Zoller,Margot. CD44 promotes progenitor homing into the thymus and T cell maturation. Journal of Leukocyte Biology 2009;85:251-261. (Link)