This site will redirect to thermofisher.com on April 7. Get details >


Anti-Human IL-13 PE

Also known as: Interleukin-13, NC30

Clone: 85BRD

RUO: For Research Use Only. Not for use in diagnostic procedures.

These products are now available on thermofisher.com. Find out more >

SKU# 12-7136

Cat. No. Size
12-7136-41 25 tests
12-7136-42 100 tests

Data for Anti-Human IL-13 PE.

Normal human peripheral blood cells were unstimulated (left) or stimulated for 5 hours with the Cell...View More

  • Data for Anti-Human IL-13 PE.
  • Data for Anti-Human IL-13 PE.
Description

Description: The 85BRD monoclonal antibody reacts with human interleukin-13 (IL-13). IL-13, also known as NC30, is a 12.5 kDa protein secreted by activated T helper cells, CD8+ T cells, and NK cells. The biological activities of IL-13 include suppression of macrophage cytotoxic activity, upregulation of IL-1RA expression and suppression of inflammatory cytokine expression.

Details
Host Mouse
Isotype IgG2b, kappa
Reactivity Human
Conjugate PE
Laser Blue Laser, Green Laser, Yellow-Green Laser
Emit 578 nm
Excite 488 - 561 nm
Reported Applications Intracellular Staining Followed by Flow Cytometric Analysis
Documentation
TDS Link Download TDS
Additional Formats
Cat. No. Name Excite Emit Application Reg.
11-7136 Anti-Human IL-13 FITC 488 nm 520 nm FC RUO
Related Products
Cat. No. Name Excite Emit Application Reg.
00-4980 Protein Transport Inhibitor Cocktail (500X) FC, FA GPR
17-0049 Anti-Human CD4 APC 633 - 647 nm 660 nm FC RUO
00-4975 Cell Stimulation Cocktail (plus protein transport inhibitors) (500X) FC, FA GPR
12-4732 Mouse IgG2b K Isotype Control PE 488 - 561 nm 578 nm FC RUO
88-8824 Intracellular Fixation & Permeabilization Buffer Set FC GPR
References

References: Divekar AA, Khanna D, Abtin F, Maranian P, Saggar R, Saggar R, Furst DE, Singh RR. Reatment with imatinib results in reduced IL-4-producing T cells, but increased CD4(+) T cells in the broncho-alveolar lavage of patients with systemic sclerosis. Clin Immunol. 2011 Dec;141(3):293-303

Griffioen M, Borghi M, Schrier PI, Osanto S, Schadendorf D. Analysis of T-cell responses in metastatic melanoma patients vaccinated with dendritic cells pulsed with tumor lysates. Cancer Immunol Immunother. 2004 Aug;53(8):715-22.

van Halteren AG, van Etten E, de Jong EC, Bouillon R, Roep BO, Mathieu C.Redirection of human autoreactive T-cells Upon interaction with dendritic cells modulated by TX527, an analog of 1,25 dihydroxyvitamin D(3). Diabetes. 2002 Jul;51(7):2119-25.

Martin S, Wolf-Eichbaum D, Duinkerken G, Scherbaum WA, Kolb H, Noordzij JG, Roep BO. Development of type 1 diabetes despite severe hereditary B-lymphocyte deficiency. N Engl J Med. 2001 Oct 4;345(14):1036-40

Chomarat P , Banchereau J. Interleukin-4 and interleukin-13: their similarities and discrepancies. Int Rev Immunol. 1998;17(1-4):1-52.


View More Products

AntigensCell TypeFormatsMiscellaneous