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Anti-Human IL-21 PE

Also known as: Interleukin-21, IL21

Clone: eBio3A3-N2 (3A3-N2)

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 12-7219

Cat. No. Size
12-7219-41 25 tests
12-7219-42 100 tests
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Data for Anti-Human IL-21 PE.

Intracellular staining of normal human peripheral blood cells treated with PMA and Ionomycin in the...View More

  • Data for Anti-Human IL-21 PE.
Description

Description: The monoclonal antibody eBio3A3-N2 reacts with human IL-21, a potent stimulator of NK and cytolytic T cells. IL-21 is a 131 amino acid protein most closely related to IL-2 and IL-15. Expression is found in CD4+ cells upon activation. In addition to its effect on NK cells, IL-21 stimulates proliferation of B-cell stimulated by crosslinking of the CD40 antigen and stimulates the proliferation of bone marrow progenitor cells and the expression of the NK-cell marker CD56 in the presence of IL-15.

Details
Host Mouse
Isotype IgG1, kappa
Reactivity Human
Conjugate PE
Laser Blue Laser, Green Laser, Yellow-Green Laser
Emit 575 nm
Excite 488 - 561 nm
Reported Applications Intracellular Staining Followed by Flow Cytometric Analysis
Documentation
TDS Link Download TDS
Additional Formats
Cat. No. Name Excite Emit Application Reg.
14-7219 Anti-Human IL-21 Purified ELISA RUO
50-7219 Anti-Human IL-21 eFluor® 660 (Alexa Fluor 647 Replacement) 633 - 647 nm 668 nm FC RUO
Related Products
Cat. No. Name Excite Emit Application Reg.
11-0049 Anti-Human CD4 FITC 488 nm 518 nm FC RUO
12-4714 Mouse IgG1 K Isotype Control PE 488 - 561 nm 575 nm FC RUO
88-8419 Human Th17 Cytokine Staining Panel FC RUO
88-8823 Intracellular Fixation & Permeabilization Buffer (plus Brefeldin A) (previously named IC Fixation & Permeabilization Buffer) FC GPR
References

References: Parrish-Novak J, et al. 2002. Interleukin-21 and the IL-21 receptor: novel effectors of NK and T cell responses. J Leukoc Biol. 72(5):856-63.

Parrish-Novak J, et al. 2000. Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function. Nature. 408(6808):57-63.

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