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Anti-Human IL-21 PE

Also known as: Interleukin-21, IL21

Clone: eBio3A3-N2 (3A3-N2)

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 12-7219

Cat. No. Size
12-7219-41 25 tests
12-7219-42 100 tests
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Data for Anti-Human IL-21 PE.

Intracellular staining of normal human peripheral blood cells treated with PMA and Ionomycin in the...View More

  • Data for Anti-Human IL-21 PE.
Description

Description: The monoclonal antibody eBio3A3-N2 reacts with human IL-21, a potent stimulator of NK and cytolytic T cells. IL-21 is a 131 amino acid protein most closely related to IL-2 and IL-15. Expression is found in CD4+ cells upon activation. In addition to its effect on NK cells, IL-21 stimulates proliferation of B-cell stimulated by crosslinking of the CD40 antigen and stimulates the proliferation of bone marrow progenitor cells and the expression of the NK-cell marker CD56 in the presence of IL-15.

Details
Host Mouse
Isotype IgG1, kappa
Reactivity Human
Conjugate PE
Laser Blue Laser, Green Laser, Yellow-Green Laser
Emit 575 nm
Excite 488 - 561 nm
Reported Applications Intracellular Staining Followed by Flow Cytometric Analysis
Documentation

For complete product information, please download the TDS or IFU document.

TDS Link Download TDS
Additional Formats
Cat. No. Name Excite Emit Application Reg.
51-7219 Anti-Human IL-21 Alexa Fluor® 647 (To Be Discontinued. Refer to Replacement Format eFluor® 660, cat. 50-7219) 633 nm 668 nm FC RUO
50-7219 Anti-Human IL-21 eFluor® 660 633 nm 668 nm FC RUO
14-7219 Anti-Human IL-21 Purified ELISA RUO
References

References: Parrish-Novak J, et al. 2002. Interleukin-21 and the IL-21 receptor: novel effectors of NK and T cell responses. J Leukoc Biol. 72(5):856-63.

Parrish-Novak J, et al. 2000. Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function. Nature. 408(6808):57-63.

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