Anti-Human IL-21 Biotin

Also known as: Interleukin-21, IL21

Clone: eBio2B2-G20 (2B2-G20)

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 13-7218

Cat. No. Size
13-7218-81 50 ug
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Data for Anti-Human IL-21 Biotin.

Standard curve of human IL-21 ELISA (cat. 88-7216). ...View More

  • Data for Anti-Human IL-21 Biotin.
Description

Description: The monoclonal antibody eBio2B2-G20 reacts with human IL-21, a potent stimulator of NK and cytolytic T cells. IL-21 is a 131 amino acid protein most closely related to IL-2 and IL-15. Expression is found in CD4+ cells upon activation. In addition to its effect on NK cells, IL-21 stimulates proliferation of B-cell stimulated by crosslinking of the CD40 antigen and stimulates the proliferation of bone marrow progenitor cells and the expression of the NK-cell marker CD56 in the presence of IL-15.

Details
Host Mouse
Isotype IgG1, kappa
Reactivity Human
Conjugate Biotin
Reported Applications ELISA Detection Antibody
Documentation
TDS Link Download TDS
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References

References: Parrish-Novak J, et al. 2000. Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function. Nature. 408(6808):57-63.

Parrish-Novak J, et al. 2002. Interleukin-21 and the IL-21 receptor: novel effectors of NK and T cell responses. J Leukoc Biol. 72(5):856-63.