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Anti-Human IL-12/IL-23 p40 PE

Also known as: Interleukin-12, IL12 / Interleukin-23, IL23

Clone: eBioHP40 (HP40, HP-40)

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 12-7235

Cat. No. Size
12-7235-42 100 tests
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Data for Anti-Human IL-12/IL-23 p40 PE.

Intracellular staining of unstimulated (left) or IFN gamma, LPS, and Monensin stimulated (right)...View More

  • Data for Anti-Human IL-12/IL-23 p40 PE.
Description

Description: The eBioHP40 antibody reacts with the p40 subunit of human IL-12 p70, and human IL-23. IL-12 is a 70 kDa heterodimeric cytokine composed of two covalently linked chains, p40 and p35, and is secreted primarily by activated monocytes, macrophages, and dendritic cells. IL-23 is a biologically-related, heterodimeric cytokine composed of disulfide-linked p40 and p19 subunits.

The eBioHP40 antibody has slightly lower background staining than C8.6 and recognizes a different epitope.

Details
Host Mouse
Isotype IgG1, kappa
Reactivity Human
Conjugate PE
Laser Blue Laser, Green Laser, Yellow-Green Laser
Emit 575 nm
Excite 488 - 561 nm
Reported Applications Intracellular Staining Followed by Flow Cytometric Analysis
Documentation
TDS Link Download TDS
Additional Formats
Cat. No. Name Excite Emit Application Reg.
50-7235 Anti-Human IL-12/IL-23 p40 eFluor® 660 633 - 647 nm 668 nm FC RUO
46-7235 Anti-Human IL-12/IL-23 p40 PerCP-eFluor® 710 488 nm 710 nm FC RUO
Related Products
Cat. No. Name Excite Emit Application Reg.
11-0149 Anti-Human CD14 FITC 488 nm FC RUO
12-4714 Mouse IgG1 K Isotype Control PE 488 - 561 nm 575 nm FC RUO
12-7123 Anti-Mouse IL-12/IL-23 p40 PE 488 - 561 nm FC RUO
12-7129 Anti-Human IL-12/IL-23 p40 PE 488 - 561 nm FC RUO
References

References:
Cho, D., et al. 1996. Enhancement of porcine natural killer cell activity by recombinant human and murine IL-12. Cell Immunol. 172: 29-34.

Aragane, Y, et al. 1994. IL-12 is expressed and released by human keratinocytes and epidermoid carcinoma cell lines. J Immunol. 153: 5366-72.

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