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Anti-Human IL-12/IL-23 p40 eFluor® 660

Clone: eBioHP40 (HP40, HP-40)

RUO: For Research Use Only. Not for use in diagnostic procedures.

Attention: Replacement format for Alexa Fluor® 647

SKU# 50-7235

Cat. No. Size
50-7235-41 25 tests
50-7235-42 100 tests
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Data for Anti-Human IL-12/IL-23 p40 eFluor® 660 (Alexa Fluor® 647 Replacement).

Staining of unstimulated (left) or stimulated (right) cultured human dendritic cells with Anti-Human...View More

  • Data for Anti-Human IL-12/IL-23 p40 eFluor® 660 (Alexa Fluor® 647 Replacement).
Description

Description: The eBioHP40 antibody reacts with the p40 subunit of human IL-12 p70, and human IL-23. IL-12 is a 70 kDa heterodimeric cytokine composed of two covalently linked chains, p40 and p35, and is secreted primarily by activated monocytes, macrophages, and dendritic cells. IL-23 is a biologically-related, heterodimeric cytokine composed of disulfide-linked p40 and p19 subunits.

The eBioHP40 antibody has slightly lower background staining than C8.6 and recognizes a different epitope.

Details
Host Mouse
Isotype IgG1, kappa
Reactivity Human
Conjugate eFluor 660
Laser Red Laser
Emit 668 nm
Excite 633 - 647 nm
Reported Applications Intracellular Staining Followed by Flow Cytometric Analysis
Documentation
TDS Link Download TDS
Additional Formats
Cat. No. Name Excite Emit Application Reg.
46-7235 Anti-Human IL-12/IL-23 p40 PerCP-eFluor® 710 488 nm 710 nm FC RUO
12-7235 Anti-Human IL-12/IL-23 p40 PE 488 - 561 nm 575 nm FC RUO
Related Products
Cat. No. Name Excite Emit Application Reg.
00-8222 IC Fixation Buffer FC GPR
00-8333 Permeabilization Buffer (10X) FC GPR
12-0118 Anti-Human CD11b PE 488 - 561 nm 575 nm FC RUO
50-4714 Mouse IgG1 K Isotype Control eFluor® 660 (Alexa Fluor® 647 Replacement) 633 - 647 nm 668 nm FC, IHC RUO
65-0863 Fixable Viability Dye eFluor® 450 FC GPR
References

References:
Cho, D., et al. 1996. Enhancement of porcine natural killer cell activity by recombinant human and murine IL-12. Cell Immunol. 172: 29-34.

Aragane, Y, et al. 1994. IL-12 is expressed and released by human keratinocytes and epidermoid carcinoma cell lines. J Immunol. 153: 5366-72.

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