Anti-Human IL-12/IL-23 p40 eFluor® 660 (Alexa Fluor® 647 Replacement)

Also known as: Interleukin-12/Interleukin-23, p40/70

Clone: C8.6

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 50-7129

Cat. No.	Size
50-7129-41	25 tests
50-7129-42	100 tests
Please inquire about custom configurations or bulk packaging.

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Normal human peripheral blood cells were unstimulated (left) or stimulated with IFN gamma and LPS...View More

Description

Description: The C8.6 antibody reacts with the p40 subunit of human IL-12 p70 and human IL-23. IL-12 is a 70 kDa heterodimeric cytokine composed of two covalently linked chains, p40 and p35, and secreted primarily by activated monocytes, macrophages, and dendritic cells. IL-23 is a biologically-related, heterodimeric cytokine composed of disulfide-linked p40 and p19 subunits.

Details

Host	Mouse
Isotype	IgG1, kappa
Reactivity	Human
Conjugate	eFluor 660
Laser	Red Laser
Emit	668 nm
Excite	633 - 647 nm
Reported Applications	Intracellular Staining Followed by Flow Cytometric Analysis

Documentation

TDS Link	Download TDS

Additional Formats

Cat. No.	Name	Excite	Emit	Application	Reg.
48-7129	Anti-Human IL-12/IL-23 p40 eFluor® 450	405 nm	450 nm	FC	RUO
13-7129	Anti-Human IL-12/IL-23 p40 Biotin			ELISA	RUO
12-7129	Anti-Human IL-12/IL-23 p40 PE	488 - 561 nm		FC	RUO
14-7129	Anti-Human IL-12/IL-23 p40 Purified			FC, FA, WB	RUO
16-7129	Anti-Human IL-12/IL-23 p40 Functional Grade Purified			ELISA, FA	RUO
53-7129	Anti-Human IL-12/IL-23 p40 Alexa Fluor® 488	488 nm	519 nm	FC	RUO

Related Products

Cat. No.	Name	Excite	Emit	Application	Reg.
00-4505	Monensin Solution (1000X)			FC	GPR
14-8319	Human IFN gamma Recombinant Protein			FA	RUO
50-4714	Mouse IgG1 K Isotype Control eFluor® 660 (Alexa Fluor® 647 Replacement)	633 - 647 nm	668 nm	FC, IHC	RUO
65-0865	Fixable Viability Dye eFluor® 780			FC	GPR
88-8823	Intracellular Fixation & Permeabilization Buffer (plus Brefeldin A) (previously named IC Fixation & Permeabilization Buffer)			FC	GPR

References

References: Cho D, Lee WJ, Halloran PJ, Trinchieri G, Kim YB. Enhancement of porcine natural killer cell activity by recombinant human and murine IL-12. Cell Immunol. 1996 Aug 25;172(1):29-34.

Aragane Y, Riemann H, Bhardwaj RS, Schwarz A, Sawada Y, Yamada H, Luger TA, Kubin M, Trinchieri G, Schwarz T. IL-12 is expressed and released by human keratinocytes and epidermoid carcinoma cell lines. J Immunol. 1994 Dec 15;153(12):5366-72.

View More Products

Antigens	Area of Biology	Cell Type	Formats
IL-12/IL-23	Cytokines, Chemokines, Growth Factors Innate Immunity	Dendritic Cells Th1 Cells	eFluor 660