Anti-Human IL-12/IL-23 p40 Alexa Fluor® 488

Also known as: Interleukin-12/Interleukin-23, p40/70

Clone: C8.6

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 53-7129

Cat. No.	Size
53-7129-41	25 tests
53-7129-42	100 tests
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Intracellular staining of unstimulated (left) or 2-hour IFN gamma and overnight LPS-stimulated...View More

Description

Description: The C8.6 antibody reacts with the p40 subunit of human IL-12 p70 and human IL-23. IL-12 is a 70 kDa heterodimeric cytokine composed of two covalently linked chains, p40 and p35, and secreted primarily by activated monocytes, macrophages, and dendritic cells. IL-23 is a biologically-related, heterodimeric cytokine composed of disulfide-linked p40 and p19 subunits.

Details

Host	Mouse
Isotype	IgG1, kappa
Reactivity	Human
Conjugate	Alexa Fluor 488
Laser	Blue Laser
Emit	519 nm
Excite	488 nm
Legal	Alexa Fluor® and Pacific Blue® are registered trademarks of and licensed under patents assigned to Molecular Probes, Inc. for research use only. This product is subject to an agreement between Molecular Probes, Inc. and eBioscience, and the manufacture, use, sale or import of this product may be subject to one or more U.S. patents, pending applications and corresponding foreign equivalents, owned by Molecular Probes, Inc. (a wholly owned subsidiary of Invitrogen Corp). The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product for life science research or as an ASR. The buyer cannot use this product for manufacturing or for any other screening (specifically including use in combination with microarrays or High Content Screening) or testing purpose, other than as an ASR. For information on purchasing a license to this product for purposes other than life science research or use as an ASR, contact Molecular Probes, Inc.
Reported Applications	Intracellular Staining Followed by Flow Cytometric Analysis

Documentation

TDS Link	Download TDS

Additional Formats

Cat. No.	Name	Excite	Emit	Application	Reg.
14-7129	Anti-Human IL-12/IL-23 p40 Purified			FC, FA, WB	RUO
16-7129	Anti-Human IL-12/IL-23 p40 Functional Grade Purified			ELISA, FA	RUO
12-7129	Anti-Human IL-12/IL-23 p40 PE	488 - 561 nm		FC	RUO
13-7129	Anti-Human IL-12/IL-23 p40 Biotin			ELISA	RUO
48-7129	Anti-Human IL-12/IL-23 p40 eFluor® 450	405 nm	450 nm	FC	RUO
50-7129	Anti-Human IL-12/IL-23 p40 eFluor® 660 (Alexa Fluor® 647 Replacement)	633 - 647 nm	668 nm	FC	RUO

Related Products

Cat. No.	Name	Excite	Emit	Application	Reg.
00-8222	IC Fixation Buffer			FC	GPR
00-8333	Permeabilization Buffer (10X)			FC	GPR
14-8319	Human IFN gamma Recombinant Protein			FA	RUO
53-4714	Mouse IgG1 K Isotype Control Alexa Fluor® 488	488 nm	519 nm	FC, ICC, IHC	RUO

References

References: Cho, D., et al. 1996. Enhancement of porcine natural killer cell activity by recombinant human and murine IL-12. Cell Immunol. 172: 29-34.

Aragane, Y, et al. 1994. IL-12 is expressed and released by human keratinocytes and epidermoid carcinoma cell lines. J Immunol. 153: 5366-72.

View More Products

Antigens	Area of Biology	Cell Type	Formats
IL-12/IL-23	Cytokines, Chemokines, Growth Factors Innate Immunity	Dendritic Cells Th1 Cells	Alexa Fluor 488