Anti-Human IL-10 eFluor® 450

Also known as: Interleukin-10, IL10

Clone: JES3-9D7

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 48-7108

Cat. No. Size
48-7108-41 25 tests
48-7108-42 100 tests
Please inquire about custom configurations or bulk packaging.

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Data for Anti-Human IL-10 eFluor® 450 (Pacific Blue® replacement).

Intracellular staining of Th2-polarized and re-stimulated (in the presence of Brefeldin A) human...View More

  • Data for Anti-Human IL-10 eFluor® 450 (Pacific Blue® replacement).
Description

Description: The JES3-9D7 monoclonal antibody reacts with human interleukin-10 (IL-10).

Details
Host Rat
Isotype IgG1, kappa
Reactivity Human
Conjugate eFluor 450
Laser Violet Laser
Emit 450 nm
Excite 405 nm
Reported Applications Intracellular Staining Followed by Flow Cytometric Analysis
Documentation
TDS Link Download TDS
Additional Formats
Cat. No. Name Excite Emit Application Reg.
50-7108 Anti-Human IL-10 eFluor® 660 (Alexa Fluor® 647 Replacement) 633 - 647 nm 668 nm FC RUO
16-7108 Anti-Human IL-10 Functional Grade Purified ELISA, FA RUO
12-7108 Anti-Human IL-10 PE 488 - 561 nm FC RUO
53-7108 Anti-Human IL-10 Alexa Fluor® 488 488 nm 519 nm FC RUO
14-7108 Anti-Human IL-10 Purified ELISA, IHC RUO
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References

References: Nowacki TM, Kuerten S, Zhang W, Shive CL, Kreher CR, Boehm BO, Lehmann PV, Tary-Lehmann M. Granzyme B production distinguishes recently activated CD8(+) memory cells from resting memory cells. Cell Immunol. 2007 May;247(1):36-48. (JES3-9D7, ELISPOT, PubMed)

Sendide K, Deghmane AE, Pechkovsky D, Av-Gay Y, Talal A, Hmama Z. Mycobacterium bovis BCG attenuates surface expression of mature class II molecules through IL-10-dependent inhibition of cathepsin S. J Immunol. 2005 Oct 15;175(8):5324-32. (JES3-9D7, FA, PubMed)

Martin M, Schifferle RE, Cuesta N, Vogel SN, Katz J, Michalek SM. Role of the phosphatidylinositol 3 kinase-Akt pathway in the regulation of IL-10 and IL-12 by Porphyromonas gingivalis lipopolysaccharide. J Immunol. 2003 Jul 15;171(2):717-25. (JES3-9D7, NU in vitro, PubMed)

Chandler SW, Rassekh CH, Rodman SM, Ducatman BS. Immunohistochemical localization of interleukin-10 in human oral and pharyngeal carcinomas. Laryngoscope. 2002 May;112(5):808-15. (JES3-9D7, IHC paraffin)

Abrams JS, Roncarolo MG, Yssel H, Andersson U, Gleich GJ, Silver JE. Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples.Immunol Rev. 1992 Jun;127:5-24.