Anti-Human IL-10 Alexa Fluor® 488

Also known as: Interleukin-10, IL10

Clone: JES3-9D7

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 53-7108

Cat. No.	Size
53-7108-41	25 tests
53-7108-42	100 tests
Please inquire about custom configurations or bulk packaging.

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Intracellular staining of Th2-polarized cells restimulated with PMA/Ionomycin (right) or...View More

Description

Description: The JES3-9D7 monoclonal antibody reacts with human interleukin-10 (IL-10).

Details

Host	Rat
Isotype	IgG1, kappa
Reactivity	Human
Conjugate	Alexa Fluor 488
Laser	Blue Laser
Emit	519 nm
Excite	488 nm
Legal	Alexa Fluor® and Pacific Blue® are registered trademarks of and licensed under patents assigned to Molecular Probes, Inc. for research use only. This product is subject to an agreement between Molecular Probes, Inc. and eBioscience, and the manufacture, use, sale or import of this product may be subject to one or more U.S. patents, pending applications and corresponding foreign equivalents, owned by Molecular Probes, Inc. (a wholly owned subsidiary of Invitrogen Corp). The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product for life science research or as an ASR. The buyer cannot use this product for manufacturing or for any other screening (specifically including use in combination with microarrays or High Content Screening) or testing purpose, other than as an ASR. For information on purchasing a license to this product for purposes other than life science research or use as an ASR, contact Molecular Probes, Inc.
Reported Applications	Intracellular Staining Followed by Flow Cytometric Analysis

Documentation

TDS Link	Download TDS

Additional Formats

Cat. No.	Name	Excite	Emit	Application	Reg.
14-7108	Anti-Human IL-10 Purified			ELISA, IHC	RUO
48-7108	Anti-Human IL-10 eFluor® 450	405 nm	450 nm	FC	RUO
50-7108	Anti-Human IL-10 eFluor® 660 (Alexa Fluor® 647 Replacement)	633 - 647 nm	668 nm	FC	RUO
12-7108	Anti-Human IL-10 PE	488 - 561 nm		FC	RUO
16-7108	Anti-Human IL-10 Functional Grade Purified			ELISA, FA	RUO

Related Products

Cat. No.	Name	Excite	Emit	Application	Reg.
12-0037	Anti-Human CD3 PE	488 - 561 nm	575 nm	FC	RUO
53-4301	Rat IgG1 K Isotype Control Alexa Fluor® 488	488 nm	519 nm	FC, ICC, IHC	RUO
53-7101	Anti-Mouse IL-10 Alexa Fluor® 488	488 nm	519 nm	FC	RUO

References

References: Nowacki TM, Kuerten S, Zhang W, Shive CL, Kreher CR, Boehm BO, Lehmann PV, Tary-Lehmann M. Granzyme B production distinguishes recently activated CD8(+) memory cells from resting memory cells. Cell Immunol. 2007 May;247(1):36-48. (JES3-9D7, ELISPOT, PubMed)

Sendide K, Deghmane AE, Pechkovsky D, Av-Gay Y, Talal A, Hmama Z. Mycobacterium bovis BCG attenuates surface expression of mature class II molecules through IL-10-dependent inhibition of cathepsin S. J Immunol. 2005 Oct 15;175(8):5324-32. (JES3-9D7, FA, PubMed)

Martin M, Schifferle RE, Cuesta N, Vogel SN, Katz J, Michalek SM. Role of the phosphatidylinositol 3 kinase-Akt pathway in the regulation of IL-10 and IL-12 by Porphyromonas gingivalis lipopolysaccharide. J Immunol. 2003 Jul 15;171(2):717-25. (JES3-9D7, NU in vitro, PubMed)

Chandler SW, Rassekh CH, Rodman SM, Ducatman BS. Immunohistochemical localization of interleukin-10 in human oral and pharyngeal carcinomas. Laryngoscope. 2002 May;112(5):808-15. (JES3-9D7, IHC paraffin)

Abrams JS, Roncarolo MG, Yssel H, Andersson U, Gleich GJ, Silver JE. Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples.Immunol Rev. 1992 Jun;127:5-24.

View More Products

Antigens	Area of Biology	Cell Type	Formats
IL-10	Adaptive Immunity Cytokines, Chemokines, Growth Factors Innate Immunity	Macrophage & Monocyte Cells T Cells Treg Cells Th2 Cells	Alexa Fluor 488