Anti-Human IFN gamma PE-Cyanine7

Also known as: Interferon gamma

Clone: 4S.B3

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 25-7319

Cat. No.	Size
25-7319-41	25 tests
25-7319-82	100 ug
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Intracellular staining of 5-hour unstimulated (left) or PMA/Ionomycin-stimulated (with Brefeldin A)...View More

Description

Description: The 4S.B3 monoclonal antibody reacts with interferon-gamma (IFN gamma). The 4S.B3 antibody is a neutralizing antibody. Human IFN gamma is a 17 kDa factor produced by activated T and NK cells and is an anti-viral and anti-parasitic cytokine. IFN gamma in synergy with other cytokines, such as TNF alpha, inhibits proliferation of normal and transformed cells. Immunomodulatory effects of IFN gamma are exerted on a wide range of cell types expressing the high affinity receptors for IFN gamma. Glycosylation of IFN gamma does not affect its biological activity.

Details

Host	Mouse
Isotype	IgG1, kappa
Reactivity	Human
Conjugate	PE-Cyanine7
Laser	Blue Laser, Green Laser, Yellow-Green Laser
Emit	775 nm
Excite	488 - 561 nm
Legal	FOR NON-COMMERCIAL RESEARCH USE ONLY. NOT FOR THERAPEUTIC OR IN VIVO APPLICATIONS. OTHER USE NEEDS LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. UNDER U.S. PATENT FOR NON-COMMERCIAL RESEARCH USE ONLY. NOT FOR THERAPEUTIC OR IN VIVO APPLICATIONS. OTHER USE NEEDS LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. UNDER U.S. PATENT # 5,268,486, 5,569,587 AND 5,627,027 AND FOREIGN EQUIVALENTS AND PENDING APPLICATIONS. THIS MATERIAL IS SUBJECT TO PROPRIETARY RIGHTS OF GE HEALTHCARE BIO-SCIENCES CORP. AND CARNEGIE MELLON UNIVERSITY AND MADE AND SOLD UNDER LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. THIS PRODUCT IS LICENSED FOR SALE ONLY FOR RESEARCH. IT IS NOT LICENSED FOR ANY OTHER USE. THERE IS NO IMPLIED LICENSE HEREUNDER FOR ANY COMMERCIAL USE. COMMERCIAL USE shall include: 1. sale, lease, license or other transfer of the material or any material derived or produced from it; 2. sale, lease, license or other grant of rights to use this Material or any material derived or produced from it; 3. use of this material to perform services for a fee for third parties. IF YOU REQUIRE A COMMERCIAL LICENSE TO USE THIS MATERIAL AND DO NOT HAVE ONE, RETURN THIS MATERIAL, UNOPENED TO EBIOSCIENCE, INC. 10255 SCIENCE CENTER DRIVE, SAN DIEGO, CALIFORNIA 92121 USA AND ANY MONEY PAID FOR THE MATERIAL WILL BE REFUNDED.
Reported Applications	Intracellular Staining Followed by Flow Cytometric Analysis

Documentation

TDS Link	Download TDS

Additional Formats

Cat. No.	Name	Excite	Emit	Application	Reg.
48-7319	Anti-Human IFN gamma eFluor® 450	405 nm	450 nm	FC	RUO
53-7319	Anti-Human IFN gamma Alexa Fluor® 488	488 nm	519 nm	FC	RUO
47-7319	Anti-Human IFN gamma APC-eFluor® 780	633 - 647 nm	780 nm	FC	RUO
45-7319	Anti-Human IFN gamma PerCP-Cyanine5.5	488 nm		FC	RUO
50-7319	Anti-Human IFN gamma eFluor® 660 (Alexa® 647 Replacement)	633 - 647 nm	668 nm	FC	RUO
12-7319	Anti-Human IFN gamma PE	488 - 561 nm	575 nm	FC	RUO
51-7319	Anti-Human IFN gamma Alexa Fluor® 647 (To be discontinued; see Cat. No. 50-7319)	633 nm	668 nm	FC	RUO
17-7319	Anti-Human IFN gamma APC	633 - 647 nm	660 nm	FC	RUO
11-7319	Anti-Human IFN gamma FITC	488 nm		FC	RUO
14-7319	Anti-Human IFN gamma Purified			FC	RUO
13-7319	Anti-Human IFN gamma Biotin			ELISA	RUO

Related Products

Cat. No.	Name	Excite	Emit	Application	Reg.
00-8222	IC Fixation Buffer			FC	GPR
00-8333	Permeabilization Buffer (10X)			FC	GPR
11-0049	Anti-Human CD4 FITC	488 nm	518 nm	FC	RUO
25-4714	Mouse IgG1 K Isotype Control PE-Cyanine7	488 - 561 nm	775 nm	FC	RUO
88-8823	Intracellular Fixation & Permeabilization Buffer (plus Brefeldin A) (previously named IC Fixation & Permeabilization Buffer)			FC	GPR

References

References: Meager A, Parti S, Barwick S, Spragg J, O'Hagan K. Detection of hybridomas secreting monoclonal antibodies to human gamma interferon using a rapid screening technique and specificity of certain monoclonal antibodies to gamma interferon. J Interferon Res. 1984 Fall;4(4):619-25.

View More Products

Antigens	Area of Biology	Cell Type	Formats
IFN gamma	Adaptive Immunity Cytokines, Chemokines, Growth Factors Innate Immunity	NK & NKT Cells T Cells Th1 Cells	PE-Cyanine7