Anti-Human IFN gamma Alexa Fluor® 488

Also known as: Interferon-gamma

Clone: 4S.B3

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 53-7319

Cat. No.	Size
53-7319-41	25 tests
53-7319-42	100 tests
Please inquire about custom configurations or bulk packaging.

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Staining of normal human peripheral blood cells stimulated with PMA/ionomycin in the presence of...View More

Description

Description: The 4S.B3 monoclonal antibody reacts with interferon-γ (IFN-γ). The 4S.B3 antibody is a neutralizing antibody. Human IFN-γ is a 17 kDa factor produced by activated T and NK cells and is an anti-viral and anti-parasitic cytokine. IFN-γ in synergy with other cytokines, such as TNF-α, inhibits proliferation of normal and transformed cells. Immunomodulatory effects of IFN-γ are exerted on a wide range of cell types expressing the high affinity receptors for IFN-γ. Glycosylation of IFN-γ does not affect its biological activity.

Details

Host	Mouse
Isotype	IgG1, kappa
Reactivity	Human
Conjugate	Alexa Fluor 488
Laser	Blue Laser
Emit	519 nm
Excite	488 nm
Legal	Alexa Fluor® and Pacific Blue® are registered trademarks of and licensed under patents assigned to Molecular Probes, Inc. for research use only. This product is subject to an agreement between Molecular Probes, Inc. and eBioscience, and the manufacture, use, sale or import of this product may be subject to one or more U.S. patents, pending applications and corresponding foreign equivalents, owned by Molecular Probes, Inc. (a wholly owned subsidiary of Invitrogen Corp). The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product for life science research or as an ASR. The buyer cannot use this product for manufacturing or for any other screening (specifically including use in combination with microarrays or High Content Screening) or testing purpose, other than as an ASR. For information on purchasing a license to this product for purposes other than life science research or use as an ASR, contact Molecular Probes, Inc.
Reported Applications	Intracellular Staining Followed by Flow Cytometric Analysis

Documentation

TDS Link	Download TDS

Additional Formats

Cat. No.	Name	Excite	Emit	Application	Reg.
25-7319	Anti-Human IFN gamma PE-Cyanine7	488 - 561 nm	775 nm	FC	RUO
45-7319	Anti-Human IFN gamma PerCP-Cyanine5.5	488 nm		FC	RUO
50-7319	Anti-Human IFN gamma eFluor® 660 (Alexa® 647 Replacement)	633 - 647 nm	668 nm	FC	RUO
12-7319	Anti-Human IFN gamma PE	488 - 561 nm	575 nm	FC	RUO
48-7319	Anti-Human IFN gamma eFluor® 450	405 nm	450 nm	FC	RUO
47-7319	Anti-Human IFN gamma APC-eFluor® 780	633 - 647 nm	780 nm	FC	RUO
14-7319	Anti-Human IFN gamma Purified			FC	RUO
51-7319	Anti-Human IFN gamma Alexa Fluor® 647 (To be discontinued; see Cat. No. 50-7319)	633 nm	668 nm	FC	RUO
11-7319	Anti-Human IFN gamma FITC	488 nm		FC	RUO
13-7319	Anti-Human IFN gamma Biotin			ELISA	RUO
17-7319	Anti-Human IFN gamma APC	633 - 647 nm	660 nm	FC	RUO

Related Products

Cat. No.	Name	Excite	Emit	Application	Reg.
53-4714	Mouse IgG1 K Isotype Control Alexa Fluor® 488	488 nm	519 nm	FC, ICC, IHC	RUO
88-7316	Human IFN gamma ELISA Ready-SET-Go!®			ELISA	RUO
88-8823	Intracellular Fixation & Permeabilization Buffer (plus Brefeldin A) (previously named IC Fixation & Permeabilization Buffer)			FC	GPR

References

References:
Meager, A., S. Parti, et al. (1984). "Detection of hybridomas secreting monoclonal antibodies to human gamma interferon using a rapid screening technique and specificity of certain monoclonal antibodies to gamma interferon." J Interferon Res 4(4): 619-25.

View More Products

Antigens	Area of Biology	Cell Type	Formats
IFN gamma	Adaptive Immunity Cytokines, Chemokines, Growth Factors Innate Immunity	NK & NKT Cells T Cells Th1 Cells	Alexa Fluor 488