Anti-human IFN-beta Antibody, Monoclonal

Also known as: Fibroblast interferon

Clone: A1

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# BMS1044BT*

Cat. No.	Size
BMS1044BT	100 ug
Please inquire about custom configurations or bulk packaging.

To enable ordering, please select your country. Cookies will need to be enabled to continue on our website. View our Privacy Policy.

Description

Description: The IFNb/A1 clone recognizes natural human IFN-beta and recombinants beta1a and beta1b. It is capable of neutralizing IFN-beta.

Interferon beta is synthesized and secreted by fibroblasts and many other cell types in response to pathogens. IFN?beta binding to type I interferon receptors induces the upregulation of IRF?7 and activation of Rnase L. IRF?7 can exert a positive feedback on IFN?beta production. RNase L cleaves both viral and cellular single stranded mRNA, thereby limiting viral replication and dissemination.

Details

Isotype	lgG1Kappa
Reactivity	Human
Conjugate	Biotin
Reported Applications	ELISA, Functional Assays, Western Blotting

Documentation

TDS Link	Download TDS

Additional Formats

Cat. No.	Name	Excite	Emit	Application	Reg.
BMS1044*	Anti-human IFN-beta			ELISA, FA, WB	RUO
BMS1044FI*	Anti-human IFN-beta Antibody, Monoclonal	488 nm	518 nm	ELISA, FA, WB	RUO

References

View More Products

Antigens	Area of Biology	Cell Type	Formats
IFN beta	Cytokines, Chemokines, Growth Factors Innate Immunity	Macrophage & Monocyte Cells	Biotin