HLA-DR PE-Cy7

Clone: L243

CE

SKU# 9025-9952

Cat. No.	Size
9025-9952-025	25 tests
9025-9952-120	120 tests
Please inquire about custom configurations or bulk packaging.

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Fluorescence profiles of normal human peripheral blood lymphocytes unstained (blue histogram) or...View More

Description

Description: The L243 mAb reacts with the human major histocompatibility complex (MHC) class II, HLA-DR. HLA-DR is expressed on the surface of human antigen presenting cells (APC) including B cells, monocytes, macrophages, DCs, and activated T cells. HLA-DR is a heterodimeric transmembrane protein composed of alpha and beta subunits and plays an important role in the presentation of peptides to CD4+ T lymphocytes.

Details

Host	Mouse
Isotype	IgG2a, kappa
Reactivity	Human
Conjugate	PE-Cyanine7
Laser	Blue Laser
Emit	760 nm
Excite	488 nm
Legal	For research (not to include in vivo research) and/or in vitro diagnostic use only. The only permitted commercial use is provision of research (not to include in vivo research) services and/or in vitro diagnostic services. Not for therapeutic or in vivo applications. Other use needs licenses which are available from GE Healthcare Bio-Sciences Corp. Under U.S. patent nos. Nos 5,268,486, 5,569,587 and 5,627,027 and foreign equivalents and pending applications. This product is subject to proprietary rights of GE Healthcare Bio-Sciences Corp. (“GE Healthcare”) and Carnegie Mellon University (“CMU”) and made and sold under license from GE Healthcare. The product bearing this label is licensed for sale only for research (not to include in vivo research) and in addition may be used to perform research (not to include in vivo research) and/or in vitro diagnostic services for third parties. It is not licensed nor are there any implied licenses for any other use including, without limitation, commercial uses unless expressly authorized by GE Healthcare in writing. If you intend to use this product commercially and you do not have a license to use this product for the intended commercial purpose, return this product, unopened to eBioscience, Inc. 10255 Science Center Drive, San Diego, California 92121 USA and any money paid for the product will be refunded.
Reported Applications	Flow Cytometric Analysis

Documentation

Instructions for Use (English)	Download English IFU
Instructions for Use (French)	Download French IFU
Instructions for Use (German)	Download German IFU
Instructions for Use (Italian)	Download Italian IFU
Instructions for Use (Spanish)	Download Spanish IFU

Additional Formats

Cat. No.	Name	Excite	Emit	Application	Reg.
9043-9952	HLA-DR PerCP	488 nm		FC	CE
9012-9952	HLA-DR PE	488 nm	575 nm	FC	CE
9048-9952	HLA-DR eFluor® 450	405 nm	450 nm	FC	CE
9046-9952	HLA-DR PerCP-eFluor® 710	488 nm	710 nm	FC	CE

References

References: Procedures for the Collection of Diagnostic Blood Specimens by Venipuncture (H3-A6), 3rd Edition published by the National Committee for Clinical Laboratory Standards.

Brodsky FM. A matrix approach to human class II histocompatibility antigens: reactions of four monoclonal antibodies with the products of nine haplotypes. Immunogenetics. 1984;19(3):179-94

Engleman EG, Warnke R, Fox RI, Dilley J, Benike CJ, Levy R. Studies of a human T lymphocyte antigen recognized by a monoclonal antibody. Proc Natl Acad Sci U S A. 1981 Mar;78(3):1791-5.

View More Products

Antigens	Area of Biology	Cell Type	Formats
HLA-DR	Adaptive Immunity Innate Immunity	B Cells Macrophage & Monocyte Cells T Cells	PE-Cyanine7