Anti-Human HLA-DR Purified

Clone: LN3

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 14-9956

Cat. No.	Size
14-9956-80	25 ug
14-9956-82	100 ug
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Staining of normal human peripheral blood cells with 0.125 ug of Purified Mouse IgG2b Isotype...View More

Description

Description: The LN3 mAb reacts with the human major histocompatibility complex (MHC) class II, HLA-DR. HLA-DR is expressed on the surface of human antigen presenting cells (APC) including B cells, monocytes, macrophages, DCs, and activated T cells. HLA-DR is a heterodimeric transmembrane protein composed of α and β subunits and plays an important role in the presentation of peptides to CD4⁺ T lymphocytes.

Details

Host	Mouse
Isotype	IgG2b, kappa
Reactivity	Human
Conjugate	Purified
Reported Applications	Flow Cytometric Analysis, Immunohistochemical Staining

Documentation

TDS Link	Download TDS

Additional Formats

Cat. No.	Name	Excite	Emit	Application	Reg.
13-9956	Anti-Human HLA-DR Biotin			FC	RUO
56-9956	Anti-Human HLA-DR Alexa Fluor® 700	633 - 647 nm	723 nm	FC	RUO
47-9956	Anti-Human HLA-DR APC-eFluor® 780	633 - 647 nm	780 nm	FC	RUO
17-9956	Anti-Human HLA-DR APC	633 - 647 nm	660 nm	FC	RUO
48-9956	Anti-Human HLA-DR eFluor® 450	405 nm	450 nm	FC	RUO
15-9956	Anti-Human HLA-DR PE-Cyanine5	488 - 561 nm		FC	RUO
25-9956	Anti-Human HLA-DR PE-Cyanine7	488 - 561 nm	775 nm	FC	RUO
45-9956	Anti-Human HLA-DR PerCP-Cyanine5.5	488 nm		FC	RUO
11-9956	Anti-Human HLA-DR FITC	488 nm		FC	RUO
12-9956	Anti-Human HLA-DR PE	488 - 561 nm		FC	RUO
93-9956	Anti-Human HLA-DR eFluor® 605NC	350 - 590 nm	605 nm	FC	RUO

Related Products

Cat. No.	Name	Excite	Emit	Application	Reg.
11-4011	Anti-Mouse IgG FITC	488 nm		FC	RUO
11-4317	Streptavidin FITC	488 nm		FC, ICC, IHC	RUO
12-4317	Streptavidin PE	488 - 561 nm		FC	RUO
13-4013	Anti-Mouse IgG Biotin			FC, ELISA, IHC, WB	RUO
14-4732	Mouse IgG2b K Isotype Control Purified			FC, ICC, IHC	RUO
17-4317	Streptavidin APC	633 - 647 nm	660 nm	FC	RUO

References

References: Fullen, D. R. and J. T. Headington. 1998. Factor XIIIa-positive dermal dendritic cells and HLA-DR expression in radial versus vertical growth-phase melanomas. J Cutan Pathol. 25(10): 553-8.

Hua, Z. X., K. E. Tanaka, et al. 1998. Immunoreactivity for LN2 and LN3 distinguishes small cell carcinomas from non-small cell carcinomas in the lung. Hum Pathol. 29(12): 1441-6.

Ioachim, H. L., S. E. Pambuccian, et al. 1996. Lymphoid monoclonal antibodies reactive with lung tumors. Diagnostic applications. Am J Surg Pathol. 20(1): 64-71.

Davey, F. R., S. Olson, et al. 1988. The immunophenotyping of extramedullary myeloid cell tumors in paraffin-embedded tissue sections. Am J Surg Pathol. 12(9): 699-707.

Norton, A. J. and P. G. Isaacson. 1987. Detailed phenotypic analysis of B-cell lymphoma using a panel of antibodies reactive in routinely fixed wax-embedded tissue. Am J Pathol. 128(2): 225-40.

View More Products

Antigens	Area of Biology	Cell Type	Formats
HLA-DR	Adaptive Immunity	B Cells Macrophage & Monocyte Cells T Cells	Purified