Anti-Human HLA-DR PE-Cyanine5

Clone: LN3

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 15-9956

Cat. No.	Size
15-9956-41	25 tests
15-9956-42	100 tests
Please inquire about custom configurations or bulk packaging.

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Staining of normal human peripheral blood cells with Mouse IgG2b Isotype Control PE-Cyanine5 (cat....View More

Description

Description: The LN3 mAb reacts with the human major histocompatibility complex (MHC) class II, HLA-DR. HLA-DR is expressed on the surface of human antigen presenting cells (APC) including B cells, monocytes, macrophages, DCs, and activated T cells. HLA-DR is a heterodimeric transmembrane protein composed of α and β subunits and plays an important role in the presentation of peptides to CD4⁺ T lymphocytes.

Details

Host	Mouse
Isotype	IgG2b, kappa
Reactivity	Human
Conjugate	PE-Cyanine5
Laser	Blue Laser, Green Laser, Yellow-Green Laser
Excite	488 - 561 nm
Legal	FOR NON-COMMERCIAL RESEARCH USE ONLY. NOT FOR THERAPEUTIC OR IN VIVO APPLICATIONS. OTHER USE NEEDS LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. UNDER U.S. PATENT FOR NON-COMMERCIAL RESEARCH USE ONLY. NOT FOR THERAPEUTIC OR IN VIVO APPLICATIONS. OTHER USE NEEDS LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. UNDER U.S. PATENT # 5,268,486, 5,569,587 AND 5,627,027 AND FOREIGN EQUIVALENTS AND PENDING APPLICATIONS. THIS MATERIAL IS SUBJECT TO PROPRIETARY RIGHTS OF GE HEALTHCARE BIO-SCIENCES CORP. AND CARNEGIE MELLON UNIVERSITY AND MADE AND SOLD UNDER LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. THIS PRODUCT IS LICENSED FOR SALE ONLY FOR RESEARCH. IT IS NOT LICENSED FOR ANY OTHER USE. THERE IS NO IMPLIED LICENSE HEREUNDER FOR ANY COMMERCIAL USE. COMMERCIAL USE shall include: 1. sale, lease, license or other transfer of the material or any material derived or produced from it; 2. sale, lease, license or other grant of rights to use this Material or any material derived or produced from it; 3. use of this material to perform services for a fee for third parties. IF YOU REQUIRE A COMMERCIAL LICENSE TO USE THIS MATERIAL AND DO NOT HAVE ONE, RETURN THIS MATERIAL, UNOPENED TO EBIOSCIENCE, INC. 10255 SCIENCE CENTER DRIVE, SAN DIEGO, CALIFORNIA 92121 USA AND ANY MONEY PAID FOR THE MATERIAL WILL BE REFUNDED.
Reported Applications	Flow Cytometric Analysis

Documentation

TDS Link	Download TDS

Additional Formats

Cat. No.	Name	Excite	Emit	Application	Reg.
17-9956	Anti-Human HLA-DR APC	633 - 647 nm	660 nm	FC	RUO
25-9956	Anti-Human HLA-DR PE-Cyanine7	488 - 561 nm	775 nm	FC	RUO
13-9956	Anti-Human HLA-DR Biotin			FC	RUO
48-9956	Anti-Human HLA-DR eFluor® 450	405 nm	450 nm	FC	RUO
12-9956	Anti-Human HLA-DR PE	488 - 561 nm		FC	RUO
56-9956	Anti-Human HLA-DR Alexa Fluor® 700	633 - 647 nm	723 nm	FC	RUO
45-9956	Anti-Human HLA-DR PerCP-Cyanine5.5	488 nm		FC	RUO
93-9956	Anti-Human HLA-DR eFluor® 605NC	350 - 590 nm	605 nm	FC	RUO
11-9956	Anti-Human HLA-DR FITC	488 nm		FC	RUO
47-9956	Anti-Human HLA-DR APC-eFluor® 780	633 - 647 nm	780 nm	FC	RUO
14-9956	Anti-Human HLA-DR Purified			FC, IHC	RUO

Related Products

Cat. No.	Name	Excite	Emit	Application	Reg.
15-4732	Mouse IgG2b K Isotype Control PE-Cyanine5	488 - 561 nm		FC	RUO

References

References: Fullen, D. R. and J. T. Headington. 1998. Factor XIIIa-positive dermal dendritic cells and HLA-DR expression in radial versus vertical growth-phase melanomas. J Cutan Pathol. 25(10): 553-8.

Hua, Z. X., K. E. Tanaka, et al. 1998. Immunoreactivity for LN2 and LN3 distinguishes small cell carcinomas from non-small cell carcinomas in the lung. Hum Pathol. 29(12): 1441-6.

Ioachim, H. L., S. E. Pambuccian, et al. 1996. Lymphoid monoclonal antibodies reactive with lung tumors. Diagnostic applications. Am J Surg Pathol. 20(1): 64-71.

Davey, F. R., S. Olson, et al. 1988. The immunophenotyping of extramedullary myeloid cell tumors in paraffin-embedded tissue sections. Am J Surg Pathol. 12(9): 699-707.

Norton, A. J. and P. G. Isaacson. 1987. Detailed phenotypic analysis of B-cell lymphoma using a panel of antibodies reactive in routinely fixed wax-embedded tissue. Am J Pathol. 128(2): 225-40.

View More Products

Antigens	Area of Biology	Cell Type	Formats
HLA-DR	Adaptive Immunity	B Cells Macrophage & Monocyte Cells T Cells	PE-Cyanine5