Anti-Human HLA-ABC Functional Grade Purified

Clone: W6/32

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 16-9983

Cat. No.	Size
16-9983-85	500 ug
Please inquire about custom configurations or bulk packaging.

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Description

Description: The W6/32 monoclonal antibody reacts with the human major histocompatibility complex (MHC) class I, HLA-A, B, C. MHC class I antigens associated with beta 2-microglobulin are expressed by all human nucleated cells and are central in cell-mediated immune response and tumor surveillance. W6/32 mAb recognizes a non-polymorphic epitope shared among products of the HLA-A, B, and C loci and immunoprecipitates both 43 kDa and 11-12 kDa chains. Crossreactivity is also seen in baboon, rhesus and cynomolgus monkey.

Details

Host	Mouse
Isotype	IgG2a, kappa
Reactivity	Human
Conjugate	Functional Grade Purified (low endotoxin, azide-free)
Reported Applications	Flow Cytometric Analysis

Documentation

TDS Link	Download TDS

Additional Formats

Cat. No.	Name	Excite	Emit	Application	Reg.
11-9983	Anti-Human HLA-ABC FITC	488 nm	518 nm	FC	RUO
15-9983	Anti-Human HLA-ABC PE-Cyanine5	488 - 561 nm		FC	RUO
12-9983	Anti-Human HLA-ABC PE	488 - 561 nm	575 nm	FC	RUO
17-9983	Anti-Human HLA-ABC APC	633 - 647 nm	660 nm	FC	RUO
14-9983	Anti-Human HLA-ABC Purified			FC, IHC, IP	RUO
13-9983	Anti-Human HLA-ABC Biotin			FC	RUO
46-9983	Anti-Human HLA-ABC PerCP-eFluor® 710	488 nm	710 nm	FC	RUO

Related Products

Cat. No.	Name	Excite	Emit	Application	Reg.
11-4011	Anti-Mouse IgG FITC	488 nm		FC	RUO
11-4317	Streptavidin FITC	488 nm		FC, ICC, IHC	RUO
12-4317	Streptavidin PE	488 - 561 nm		FC	RUO
13-4013	Anti-Mouse IgG Biotin			FC, ELISA, IHC, WB	RUO
16-4724	Mouse IgG2a K Isotype Control Functional Grade Purified			FC	RUO
17-4317	Streptavidin APC	633 - 647 nm	660 nm	FC	RUO

References

References: Barnstable, C. J., W. F. Bodmer, et al. 1978. Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for genetic analysis. Cell 14(1): 9-20.

Koene G, Arts-Hilkes, et al.2004. High level of aneuploidy of chromosome 6 by FISH analysis of head and neck squamous cell carcinoma: limited applicability of LOH analysis to define HLA loss. Hum Immunol. 65(12):1455-62. (IHC frozen, PubMed)

Goldman-Wohl D, Ariel I, et al. 2001. A study of human leukocyte antigen G expression in hydatidiform moles. Am J Obstet Gynecol. 185(2):476-80. (IHC frozen, PubMed)

Stern PL, Beresford N, et al. 1987. Class I-like MHC molecules expressed by baboon placental syncytiotrophoblast. J Immunol. 138(4):1088-91. (baboon cross-reactivity, PubMed)

View More Products

Antigens	Area of Biology	Cell Type	Formats
HLA-ABC	Adaptive Immunity	Macrophage & Monocyte Cells	Functional Grade Purified