Recombinant Human GM-CSF

Description: Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) is a potent species-specific stimulator of bone marrow cells. GM-CSF is produced by a number of different cell types in response to cytokine or inflammatory stimuli. On mature hematopoietic cells, GM-CSF is a survival factor for and activates the effector functions of granulocytes, monocytes/macrophages, and eosinophils. Human recombinant GM-CSF is a 14.5 kDa protein containing 127 amino acid residues.

Citations: von Lilienfeld-Toal,M.; Sievers,E.; Bodemuller,V.; Mihailescu,C.; Marten,A.; Gorschluter,M.; Schmidt-Wolf,I.G.H.. Coculture with dendritic cells promotes proliferation but not cytotoxic activity of @c/@d T cells. Immunology letters 2005;99:103-108. (Link)