Description: The SN4 monoclonal antibody reacts with human CD9. CD9 is a 24 kDa member of the tetraspanin family, whose members are characterized by the presence of 4 hydrophobic transmembrane domains. CD9 is expressed in platelets, eosinophils, basophils, pre-B cells, activated T cells and neural cell lines. In platelets, CD9 is expressed in alpha-granules and, through association with the integrin alpha IIb/beta III, plays a role in platelet aggregation.
