Anti-Human CD8a Purified

Also known as: CD8 alpha, leu-2a

Clone: HIT8a

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 14-0089

Cat. No.	Size
14-0089-80	25 ug
14-0089-82	100 ug
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Staining of normal human peripheral blood cells with Anti-Human CD8a FITC (left) and PE (right). ...View More

Description

Description: The HIT8a monoclonal antibody reacts with the human CD8a molecule, an approximately 32-34 kDa cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha/beta) or as a homodimer (CD8 alpha/alpha). A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class I and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells.

Details

Host	Mouse
Isotype	IgG1, kappa
Reactivity	Human
Conjugate	Purified
Reported Applications	Flow Cytometric Analysis, Immunohistochemical Staining of Frozen Tissue Sections

Documentation

TDS Link	Download TDS

Additional Formats

Cat. No.	Name	Excite	Emit	Application	Reg.
16-0089	Anti-Human CD8a Functional Grade Purified			FC	RUO
12-0089	Anti-Human CD8a PE	488 - 561 nm	575 nm	FC	RUO
13-0089	Anti-Human CD8a Biotin			FC	RUO
11-0089	Anti-Human CD8a FITC	488 nm	518 nm	FC	RUO

Related Products

Cat. No.	Name	Excite	Emit	Application	Reg.
11-4011	Anti-Mouse IgG FITC	488 nm		FC	RUO
14-4714	Mouse IgG1 K Isotype Control Purified			FC, ICC, IHC, IP, WB	RUO

References

References: Schlossman, S., L. Bloumsell, et al. eds. 1995. Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press. New York.

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Antigens	Area of Biology	Cell Type	Formats
CD8a	Adaptive Immunity	NK & NKT Cells T Cells	Purified