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Anti-Human CD8a PE-Cyanine7

Also known as: CD8 alpha, leu-2a

Clone: RPA-T8

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 25-0088

Cat. No. Size
25-0088-41 25 tests
25-0088-42 100 tests
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Data for Anti-Human CD8a PE-Cy7.

Staining of normal human peripheral blood cells with staining buffer (autofluorescence) (open...View More

  • Data for Anti-Human CD8a PE-Cy7.
Description

Description: The RPA-T8 monoclonal antibody reacts with the human CD8a molecule, an approximately 32-34 kDa cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha/beta) or as a homodimer (CD8 alpha/alpha). A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class I and through its association with protein tyrosine kinase p56lck plays a role in T-cell development and activation of mature T cells.

Details
Host Mouse
Isotype IgG1, kappa
Reactivity Human
Conjugate PE-Cyanine7
Laser Blue Laser, Green Laser, Yellow-Green Laser
Emit 775 nm
Excite 488 - 561 nm
Legal FOR NON-COMMERCIAL RESEARCH USE ONLY. NOT FOR THERAPEUTIC OR IN VIVO APPLICATIONS. OTHER USE NEEDS LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. UNDER U.S. PATENT FOR NON-COMMERCIAL RESEARCH USE ONLY. NOT FOR THERAPEUTIC OR IN VIVO APPLICATIONS. OTHER USE NEEDS LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. UNDER U.S. PATENT # 5,268,486, 5,569,587 AND 5,627,027 AND FOREIGN EQUIVALENTS AND PENDING APPLICATIONS. THIS MATERIAL IS SUBJECT TO PROPRIETARY RIGHTS OF GE HEALTHCARE BIO-SCIENCES CORP. AND CARNEGIE MELLON UNIVERSITY AND MADE AND SOLD UNDER LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. THIS PRODUCT IS LICENSED FOR SALE ONLY FOR RESEARCH. IT IS NOT LICENSED FOR ANY OTHER USE. THERE IS NO IMPLIED LICENSE HEREUNDER FOR ANY COMMERCIAL USE. COMMERCIAL USE shall include: 1. sale, lease, license or other transfer of the material or any material derived or produced from it; 2. sale, lease, license or other grant of rights to use this Material or any material derived or produced from it; 3. use of this material to perform services for a fee for third parties. IF YOU REQUIRE A COMMERCIAL LICENSE TO USE THIS MATERIAL AND DO NOT HAVE ONE, RETURN THIS MATERIAL, UNOPENED TO EBIOSCIENCE, INC. 10255 SCIENCE CENTER DRIVE, SAN DIEGO, CALIFORNIA 92121 USA AND ANY MONEY PAID FOR THE MATERIAL WILL BE REFUNDED.
Reported Applications Flow Cytometric Analysis
Documentation
TDS Link Download TDS
Additional Formats
Cat. No. Name Excite Emit Application Reg.
94-0088 Anti-Human CD8a eFluor® 625NC 350 - 610 nm 625 nm FC RUO
45-0088 Anti-Human CD8a PerCP-Cyanine5.5 488 nm FC RUO
11-0088 Anti-Human CD8a FITC 488 nm FC RUO
12-0088 Anti-Human CD8a PE 488 - 561 nm 575 nm FC RUO
15-0088 Anti-Human CD8a PE-Cyanine5 488 - 561 nm FC RUO
47-0088 Anti-Human CD8a APC-eFluor® 780 633 - 647 nm 780 nm FC RUO
95-0088 Anti-Human CD8a eFluor® 650NC 350 - 635 nm 650 nm FC RUO
93-0088 Anti-Human CD8a eFluor® 605NC 350 - 590 nm 605 nm FC RUO
35-0088 Anti-Human CD8a PE-Cyanine5.5 488 - 567 nm 690 nm FC RUO
17-0088 Anti-Human CD8a APC 633 - 647 nm 660 nm FC RUO
14-0088 Anti-Human CD8a Purified FC, IHC RUO
48-0088 Anti-Human CD8a eFluor® 450 405 nm 450 nm FC RUO
58-0088 Anti-Human CD8a Alexa Fluor® 532 532 nm 561 nm FC RUO
56-0088 Anti-Human CD8a Alexa Fluor® 700 633 - 647 nm 723 nm FC RUO
Related Products
Cat. No. Name Excite Emit Application Reg.
12-0049 Anti-Human CD4 PE 488 - 561 nm 575 nm FC RUO
12-0089 Anti-Human CD8a PE 488 - 561 nm 575 nm FC RUO
25-4714 Mouse IgG1 K Isotype Control PE-Cyanine7 488 - 561 nm 775 nm FC RUO
References

References:
Knapp, W., B. Dorken, et al. eds. (1989). Leucocyte Typing IV: White Cell Differentiation Antigens. Oxford University Press. New York.
Schlossman, S., L. Bloumsell, et al. eds. (1995). Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press. New York.

Kishimoto, T., A.E.G., von dem Borne, et al. eds. (1998). Leucocyte Typing VI: White Cell Differentiation Antigens. Garland Publishing, Inc. London.

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