Anti-Human CD82 Purified

Description: The 53H5 monoclonal antibody reacts with human CD82, a 50-53 kDa protein belonging to the tetra-span (TM4) transmembrane proteins. CD82 is expressed broadly by the majority of hematopoietic lineages, but not erythrocytes. Activation of T and B lymphocytes upregulates CD82 expression. CD82 is also expressed by epithelial and endothelial cells and fibroblasts.

References: Shibagaki N, Hanada K, Yamaguchi S, Yamashita H, Shimada S, Hamada H. Functional analysis of CD82 in the early phase of T cell activation: roles in cell adhesion and signal transduction. Eur J Immunol. 1998 Apr;28(4):1125-33. (53H5, FA, PubMed)