Anti-Human CD80 (B7-1) PE-Cyanine5

Also known as: B71, BB1

Clone: 2D10.4

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 15-0809

Cat. No.	Size
15-0809-41	25 tests
15-0809-42	100 tests
Please inquire about custom configurations or bulk packaging.

To enable ordering, please select your country. Cookies will need to be enabled to continue on our website. View our Privacy Policy.

Staining of normal human peripheral blood cells with Mouse IgG1 K Isotype Control PE-Cyanine5 (cat....View More

Description

Description: The 2D10.4 monoclonal antibody reacts with human CD80 (B7-1), a 60 kDa member of the Ig superfamily. CD80 is expressed by activated B cells, macrophages and dendritic cells. In addition, activated T cells express this antigen. CD80 has high affinity for binding to two T cell surface antigens, CD28 and CD152 (CTLA-4). The interaction of CD28 and CD152 with CD80 is crucial in T-B cell communication leading to activation of T and B cells, respectively.

Details

Host	Mouse
Isotype	IgG1, kappa
Reactivity	Human
Conjugate	PE-Cyanine5
Laser	Blue Laser, Green Laser, Yellow-Green Laser
Excite	488 - 561 nm
Legal	FOR NON-COMMERCIAL RESEARCH USE ONLY. NOT FOR THERAPEUTIC OR IN VIVO APPLICATIONS. OTHER USE NEEDS LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. UNDER U.S. PATENT FOR NON-COMMERCIAL RESEARCH USE ONLY. NOT FOR THERAPEUTIC OR IN VIVO APPLICATIONS. OTHER USE NEEDS LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. UNDER U.S. PATENT # 5,268,486, 5,569,587 AND 5,627,027 AND FOREIGN EQUIVALENTS AND PENDING APPLICATIONS. THIS MATERIAL IS SUBJECT TO PROPRIETARY RIGHTS OF GE HEALTHCARE BIO-SCIENCES CORP. AND CARNEGIE MELLON UNIVERSITY AND MADE AND SOLD UNDER LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. THIS PRODUCT IS LICENSED FOR SALE ONLY FOR RESEARCH. IT IS NOT LICENSED FOR ANY OTHER USE. THERE IS NO IMPLIED LICENSE HEREUNDER FOR ANY COMMERCIAL USE. COMMERCIAL USE shall include: 1. sale, lease, license or other transfer of the material or any material derived or produced from it; 2. sale, lease, license or other grant of rights to use this Material or any material derived or produced from it; 3. use of this material to perform services for a fee for third parties. IF YOU REQUIRE A COMMERCIAL LICENSE TO USE THIS MATERIAL AND DO NOT HAVE ONE, RETURN THIS MATERIAL, UNOPENED TO EBIOSCIENCE, INC. 10255 SCIENCE CENTER DRIVE, SAN DIEGO, CALIFORNIA 92121 USA AND ANY MONEY PAID FOR THE MATERIAL WILL BE REFUNDED.
Reported Applications	Flow Cytometric Analysis

Documentation

TDS Link	Download TDS

Additional Formats

Cat. No.	Name	Excite	Emit	Application	Reg.
13-0809	Anti-Human CD80 (B7-1) Biotin			FC	RUO
12-0809	Anti-Human CD80 (B7-1) PE	488 - 561 nm	575 nm	FC	RUO
11-0809	Anti-Human CD80 (B7-1) FITC	488 nm	518 nm	FC	RUO
46-0809	Anti-Human CD80 (B7-1) PerCP-eFluor® 710	488 nm	710 nm	FC	RUO
14-0809	Anti-Human CD80 (B7-1) Purified			FC	RUO
16-0809	Anti-Human CD80 (B7-1) Functional Grade Purified			FC, FA	RUO

Related Products

Cat. No.	Name	Excite	Emit	Application	Reg.
15-4714	Mouse IgG1 K Isotype Control PE-Cyanine5	488 - 561 nm		FC	RUO

References

References: Bashuda, H., Kimikawa, M., Seino, K., Kato, Y., Ono, F., Shimizu, A., Yagita, H., Teraoka, S., and K. Okumura. 2005. Renal allograft rejection is prevented by adoptive transfer of anergic T cells in nonhuman primates. J Clin Invest.115:1896-1902. (2D10.4, FA, PubMed)

Kishimoto, T., A.E.G., von dem Borne, et al. eds. 1998. Leucocyte Typing VI: White Cell Differentiation Antigens. Garland Publishing Inc. London.

View More Products

Antigens	Area of Biology	Cell Type	Formats
CD80 (B7-1)	Adaptive Immunity Innate Immunity	B Cells Dendritic Cells Macrophage & Monocyte Cells T Cells	PE-Cyanine5