CD8 PE-Cy7

Also known as: Leu-2a

Clone: SK1

CE

SKU# 9025-0087

Cat. No.	Size
9025-0087-025	25 tests
9025-0087-120	120 tests
Please inquire about custom configurations or bulk packaging.

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Fluorescence profiles of normal human peripheral blood lymphocytes unstained (blue histogram) or...View More

Description

Description: The SK1 monoclonal antibody reacts with the human CD8 alpha molecule, an approximately 32-34 kDa cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha/beta) or as a homodimer (CD8 alpha/alpha). A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8 alpha. CD8 binds to MHC class I and through its association with protein tyrosine kinase p56 lck plays a role in T-cell development and activation of mature T cells.

Details

Host	Mouse
Isotype	IgG1, kappa
Reactivity	Human
Conjugate	PE-Cyanine7
Laser	Blue Laser
Emit	760 nm
Excite	488 nm
Legal	For research (not to include in vivo research) and/or in vitro diagnostic use only. The only permitted commercial use is provision of research (not to include in vivo research) services and/or in vitro diagnostic services. Not for therapeutic or in vivo applications. Other use needs licenses which are available from GE Healthcare Bio-Sciences Corp. Under U.S. patent nos. Nos 5,268,486, 5,569,587 and 5,627,027 and foreign equivalents and pending applications. This product is subject to proprietary rights of GE Healthcare Bio-Sciences Corp. (“GE Healthcare”) and Carnegie Mellon University (“CMU”) and made and sold under license from GE Healthcare. The product bearing this label is licensed for sale only for research (not to include in vivo research) and in addition may be used to perform research (not to include in vivo research) and/or in vitro diagnostic services for third parties. It is not licensed nor are there any implied licenses for any other use including, without limitation, commercial uses unless expressly authorized by GE Healthcare in writing. If you intend to use this product commercially and you do not have a license to use this product for the intended commercial purpose, return this product, unopened to eBioscience, Inc. 10255 Science Center Drive, San Diego, California 92121 USA and any money paid for the product will be refunded.
Reported Applications	Flow Cytometric Analysis

Documentation

Instructions for Use (English)	Download English IFU
Instructions for Use (French)	Download French IFU
Instructions for Use (German)	Download German IFU
Instructions for Use (Italian)	Download Italian IFU
Instructions for Use (Spanish)	Download Spanish IFU

Additional Formats

Cat. No.	Name	Excite	Emit	Application	Reg.
9017-0087	CD8 APC	633 - 647 nm	660 nm	FC	CE
9048-0087	CD8 eFluor® 450	405 nm	450 nm	FC	CE
9012-0087	CD8 PE	488 nm	575 nm	FC	CE
9043-0087	CD8 PerCP	488 nm		FC	CE
9047-0087	CD8 APC-eFluor® 780	633 - 647 nm	780 nm	FC	CE
9011-0087	CD8 FITC	488 nm	518 nm	FC	CE

References

References: Procedures for the Collection of Diagnostic Blood Specimens by Venipuncture (H3-A6), 3rd Edition published by the National Committee for Clinical Laboratory Standards.

Campanelli R, Palermo B, et al. Human CD8 co-receptor is strictly involved in MHC-peptide tetramer-TCR binding and T cell activation. International Immunology. 2002 May; 14(1):39-44.

Bernard A, Boumsell L, Hill C. Joint report of the first international workshop on human leucocyte differentiation antigens by the investigators of the participating laboratories. In: Bernard A, Boumsell L, Dausset J, Milstein C, Schlossman SF, eds. Leucocyte Typing. New York, NY: Springer-Verlag; 1984:9-108.

View More Products

Antigens	Cell Type	Formats
CD8	Dendritic Cells NK & NKT Cells T Cells	PE-Cyanine7