Anti-Human CD54 (ICAM-1) PE

Description: The HA58 monoclonal antibody reacts with human CD54 (InterCellular Adhesion Molecule-1, ICAM-1), a 90-110 kDa transmembrane glycoprotein expressed by monocytes, lymphocytes and endothelial cells. Expression of CD54 is upregulated on activated lymphocytes. Interaction of CD54 with its ligand CD11a is important in the inflammatory response.

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Kishimoto, T., H. Kikutani, et al., eds. 1998. Leucocyte Typing VI: White Cell Differentiation Antigens. Garland Publishing Inc. London.

Kanwar JR, Berg RW, et al. 2003. Requirements for ICAM-1 immunogene therapy of lymphoma. Cancer Gene Ther. 10(6):468-76. (WB, PubMed)

Bao J, Sato K, et al. 2001. PR-39 and PR-11 peptides inhibit ischemia-reperfusion injury by blocking proteasome-mediated I kappa B alpha degradation. Am J Physiol Heart Circ Physiol. 281(6):H2612-8. (WB, PubMed)

Davis DM, Chiu I, et al. 1999. The human natural killer cell immune synapse. Proc Natl Acad Sci U S A. 96(26):15062-7. (IHC, PubMed)