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Fluorescence profiles of normal human peripheral blood lymphocytes unstained (blue histogram) or...View More
Description: The 2D1 monoclonal antibody reacts with all isoforms of human CD45, also known as Leukocyte Common Antigen (LCA). CD45 is expressed by all hematopoietic cells excluding circulating erythrocytes and platelets. The cytoplasmic portion of CD45 has tyrosine phosphatase enzymatic activity and plays an important role in activation of lymphocytes.
References: Schwinzer R. Cluster report: CD45/CD45R. In: Knapp W, Dörken B, Gilks WR, et al., eds. LeucocyteTyping IV: White Cell Differentiation Antigens. New York, NY: Oxford University Press; 1989:628-634.
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