Anti-Human CD45 PerCP-Cyanine5.5

Also known as: Leukocyte Common Antigen, LCA, Ly-5

Clone: HI30

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 45-0459

Cat. No. Size
45-0459-42 100 tests
45-0459-41 25 tests
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Data for Anti-Human CD45 PerCP-Cy5.5 (PE-Cy5.5 replacement).

Staining of normal human peripheral blood cells with staining buffer (autofluorescence) (open...View More

  • Data for Anti-Human CD45 PerCP-Cy5.5 (PE-Cy5.5 replacement).
Description

Description: The HI30 monoclonal antibody reacts with all isoforms of human CD45, also known as Leukocyte Common Antigen (LCA). CD45 is expressed by all hematopoietic cells excluding circulating erythrocytes and platelets. The cytoplasmic portion of CD45 has tyrosine phosphatase enzymatic activity and plays an important role in activation of lymphocytes.

Details
Host Mouse
Isotype IgG1, kappa
Reactivity Human
Conjugate PerCP-Cyanine5.5
Laser Blue Laser
Excite 488 nm
Legal FOR NON-COMMERCIAL RESEARCH USE ONLY. NOT FOR THERAPEUTIC OR IN VIVO APPLICATIONS. OTHER USE NEEDS LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. UNDER U.S. PATENT FOR NON-COMMERCIAL RESEARCH USE ONLY. NOT FOR THERAPEUTIC OR IN VIVO APPLICATIONS. OTHER USE NEEDS LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. UNDER U.S. PATENT # 5,268,486, 5,569,587 AND 5,627,027 AND FOREIGN EQUIVALENTS AND PENDING APPLICATIONS. THIS MATERIAL IS SUBJECT TO PROPRIETARY RIGHTS OF GE HEALTHCARE BIO-SCIENCES CORP. AND CARNEGIE MELLON UNIVERSITY AND MADE AND SOLD UNDER LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. THIS PRODUCT IS LICENSED FOR SALE ONLY FOR RESEARCH. IT IS NOT LICENSED FOR ANY OTHER USE. THERE IS NO IMPLIED LICENSE HEREUNDER FOR ANY COMMERCIAL USE. COMMERCIAL USE shall include: 1. sale, lease, license or other transfer of the material or any material derived or produced from it; 2. sale, lease, license or other grant of rights to use this Material or any material derived or produced from it; 3. use of this material to perform services for a fee for third parties. IF YOU REQUIRE A COMMERCIAL LICENSE TO USE THIS MATERIAL AND DO NOT HAVE ONE, RETURN THIS MATERIAL, UNOPENED TO EBIOSCIENCE, INC. 10255 SCIENCE CENTER DRIVE, SAN DIEGO, CALIFORNIA 92121 USA AND ANY MONEY PAID FOR THE MATERIAL WILL BE REFUNDED.
Reported Applications Flow Cytometric Analysis
Documentation
TDS Link Download TDS
Additional Formats
Cat. No. Name Excite Emit Application Reg.
14-0459 Anti-Human CD45 Purified FC, IHC RUO
13-0459 Anti-Human CD45 Biotin FC RUO
25-0459 Anti-Human CD45 PE-Cyanine7 488 - 561 nm 775 nm FC RUO
15-0459 Anti-Human CD45 PE-Cyanine5 488 - 561 nm FC RUO
17-0459 Anti-Human CD45 APC 633 - 647 nm 660 nm FC RUO
93-0459 Anti-Human CD45 eFluor® 605NC 350 - 590 nm 605 nm FC RUO
58-0459 Anti-Human CD45 Alexa Fluor® 532 532 nm 561 nm FC RUO
19-0459 Anti-Human CD45 Cy5 633 - 647 nm 670 nm FC RUO
35-0459 Anti-Human CD45 PE-Cyanine5.5 488 - 567 nm 690 nm FC RUO
12-0459 Anti-Human CD45 PE 488 - 561 nm 575 nm FC RUO
48-0459 Anti-Human CD45 eFluor® 450 405 nm 450 nm FC RUO
47-0459 Anti-Human CD45 APC-eFluor® 780 633 - 647 nm 780 nm FC RUO
46-0459 Anti-Human CD45 PerCP-eFluor® 710 488 nm 710 nm FC RUO
11-0459 Anti-Human CD45 FITC 488 nm 518 nm FC RUO
Related Products
Cat. No. Name Excite Emit Application Reg.
45-4714 Mouse IgG1 K Isotype Control PerCP-Cyanine5.5 488 nm FC RUO
References

References: Ninomiya M, Abe A, Katsumi A, Xu J, Ito M, Arai F, Suda T, Ito M, Kiyoi H, Kinoshita T, Naoe T. Homing, proliferation and survival sites of human leukemia cells in vivo in immunodeficient mice. Leukemia. 2007 Jan;21(1):136-42.(HI30, IF frozen)

Bouma-ter Steege JC, Baeten CI, Thijssen VL, Satijn SA, Verhoeven IC, Hillen HF, Wagstaff J, Griffioen AW.Angiogenic profile of breast carcinoma determines leukocyte infiltration. Clin Cancer Res. 2004 Nov 1;10(21):7171-8. (HI30, IHC frozen)

Knapp, W., B. Dorken, et al. eds. (1989). Leucocyte Typing IV: White Cell Differentiation Antigens. Oxford University Press. New York.