Anti-Human CD45 PerCP-Cyanine5.5

Also known as: LCA

Clone: 2D1

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 45-9459

Cat. No.	Size
45-9459-41	25 tests
45-9459-42	100 tests
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Staining of normal human peripheral blood cells with Mouse IgG1 K Isotype Control PerCP-Cyanine5.5...View More

Description

Description: The 2D1 monoclonal antibody reacts with all isoforms of human CD45, also known as Leukocyte Common Antigen (LCA). CD45 is expressed by all hematopoietic cells excluding circulating erythrocytes and platelets. The cytoplasmic portion of CD45 has tyrosine phosphatase enzymatic activity and plays an important role in activation of lymphocytes.

Details

Host	Mouse
Isotype	IgG1, kappa
Reactivity	Human
Conjugate	PerCP-Cyanine5.5
Laser	Blue Laser
Excite	488 nm
Legal	FOR NON-COMMERCIAL RESEARCH USE ONLY. NOT FOR THERAPEUTIC OR IN VIVO APPLICATIONS. OTHER USE NEEDS LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. UNDER U.S. PATENT FOR NON-COMMERCIAL RESEARCH USE ONLY. NOT FOR THERAPEUTIC OR IN VIVO APPLICATIONS. OTHER USE NEEDS LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. UNDER U.S. PATENT # 5,268,486, 5,569,587 AND 5,627,027 AND FOREIGN EQUIVALENTS AND PENDING APPLICATIONS. THIS MATERIAL IS SUBJECT TO PROPRIETARY RIGHTS OF GE HEALTHCARE BIO-SCIENCES CORP. AND CARNEGIE MELLON UNIVERSITY AND MADE AND SOLD UNDER LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. THIS PRODUCT IS LICENSED FOR SALE ONLY FOR RESEARCH. IT IS NOT LICENSED FOR ANY OTHER USE. THERE IS NO IMPLIED LICENSE HEREUNDER FOR ANY COMMERCIAL USE. COMMERCIAL USE shall include: 1. sale, lease, license or other transfer of the material or any material derived or produced from it; 2. sale, lease, license or other grant of rights to use this Material or any material derived or produced from it; 3. use of this material to perform services for a fee for third parties. IF YOU REQUIRE A COMMERCIAL LICENSE TO USE THIS MATERIAL AND DO NOT HAVE ONE, RETURN THIS MATERIAL, UNOPENED TO EBIOSCIENCE, INC. 10255 SCIENCE CENTER DRIVE, SAN DIEGO, CALIFORNIA 92121 USA AND ANY MONEY PAID FOR THE MATERIAL WILL BE REFUNDED.
Reported Applications	Flow Cytometric Analysis

Documentation

TDS Link	Download TDS

Additional Formats

Cat. No.	Name	Excite	Emit	Application	Reg.
12-9459	Anti-Human CD45 PE	488 - 561 nm	575 nm	FC	RUO
11-9459	Anti-Human CD45 FITC	488 nm	518 nm	FC	RUO
48-9459	Anti-Human CD45 eFluor® 450	405 nm	450 nm	FC	RUO
17-9459	Anti-Human CD45 APC	633 - 647 nm	660 nm	FC	RUO

Related Products

Cat. No.	Name	Excite	Application	Reg.
45-0451	Anti-Mouse CD45 PerCP-Cyanine5.5	488 nm	FC	RUO
45-0459	Anti-Human CD45 PerCP-Cyanine5.5	488 nm	FC	RUO
45-4714	Mouse IgG1 K Isotype Control PerCP-Cyanine5.5	488 nm	FC	RUO

References

References: Bradstock K.F., Janossy G., Pizzolo G., Hoffbrand A.V., McMichael A., Pilch J.R., Milstein C., Beverley P., Bollum F.J. Subpopulations of normal and leukemic human thymocytes: an analysis with the use of monoclonal antibodies. J Natl Cancer Inst. 1980 Jul; 65(1):33-42.

Tchilian E.Z., Wallace D.L., Wells R.S., Flower D.R., Morgan G., Beverley P.C. A deletion in the gene encoding the CD45 antigen in a patient with SCID. J Immunol. 2001 Jan 15;166(2):1308-13.

View More Products

Antigens	Area of Biology	Cell Type	Formats
CD45	Adaptive Immunity Cell Signaling	B Cells Macrophage & Monocyte Cells NK & NKT Cells T Cells	PerCP-Cyanine5.5