Anti-Human CD45 PE-Cyanine5

Also known as: Leukocyte Common Antigen, LCA, Ly-5

Clone: HI30

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 15-0459

Cat. No.	Size
15-0459-41	25 tests
15-0459-42	100 tests
Please inquire about custom configurations or bulk packaging.

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Staining of normal human peripheral blood cells with Mouse IgG1 K Isotype Control PE-Cyanine5 (cat....View More

Description

Description: The HI30 monoclonal antibody reacts with all isoforms of human CD45, also known as Leukocyte Common Antigen (LCA). CD45 is expressed by all hematopoietic cells excluding circulating erythrocytes and platelets. The cytoplasmic portion of CD45 has tyrosine phosphatase enzymatic activity and plays an important role in activation of lymphocytes.

Details

Host	Mouse
Isotype	IgG1, kappa
Reactivity	Human
Conjugate	PE-Cyanine5
Laser	Blue Laser, Green Laser, Yellow-Green Laser
Excite	488 - 561 nm
Legal	FOR NON-COMMERCIAL RESEARCH USE ONLY. NOT FOR THERAPEUTIC OR IN VIVO APPLICATIONS. OTHER USE NEEDS LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. UNDER U.S. PATENT FOR NON-COMMERCIAL RESEARCH USE ONLY. NOT FOR THERAPEUTIC OR IN VIVO APPLICATIONS. OTHER USE NEEDS LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. UNDER U.S. PATENT # 5,268,486, 5,569,587 AND 5,627,027 AND FOREIGN EQUIVALENTS AND PENDING APPLICATIONS. THIS MATERIAL IS SUBJECT TO PROPRIETARY RIGHTS OF GE HEALTHCARE BIO-SCIENCES CORP. AND CARNEGIE MELLON UNIVERSITY AND MADE AND SOLD UNDER LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. THIS PRODUCT IS LICENSED FOR SALE ONLY FOR RESEARCH. IT IS NOT LICENSED FOR ANY OTHER USE. THERE IS NO IMPLIED LICENSE HEREUNDER FOR ANY COMMERCIAL USE. COMMERCIAL USE shall include: 1. sale, lease, license or other transfer of the material or any material derived or produced from it; 2. sale, lease, license or other grant of rights to use this Material or any material derived or produced from it; 3. use of this material to perform services for a fee for third parties. IF YOU REQUIRE A COMMERCIAL LICENSE TO USE THIS MATERIAL AND DO NOT HAVE ONE, RETURN THIS MATERIAL, UNOPENED TO EBIOSCIENCE, INC. 10255 SCIENCE CENTER DRIVE, SAN DIEGO, CALIFORNIA 92121 USA AND ANY MONEY PAID FOR THE MATERIAL WILL BE REFUNDED.
Reported Applications	Flow Cytometric Analysis

Documentation

TDS Link	Download TDS

Additional Formats

Cat. No.	Name	Excite	Emit	Application	Reg.
12-0459	Anti-Human CD45 PE	488 - 561 nm	575 nm	FC	RUO
47-0459	Anti-Human CD45 APC-eFluor® 780	633 - 647 nm	780 nm	FC	RUO
48-0459	Anti-Human CD45 eFluor® 450	405 nm	450 nm	FC	RUO
45-0459	Anti-Human CD45 PerCP-Cyanine5.5	488 nm		FC	RUO
14-0459	Anti-Human CD45 Purified			FC, IHC	RUO
58-0459	Anti-Human CD45 Alexa Fluor® 532	532 nm	561 nm	FC	RUO
19-0459	Anti-Human CD45 Cy5	633 - 647 nm	670 nm	FC	RUO
17-0459	Anti-Human CD45 APC	633 - 647 nm	660 nm	FC	RUO
25-0459	Anti-Human CD45 PE-Cyanine7	488 - 561 nm	775 nm	FC	RUO
11-0459	Anti-Human CD45 FITC	488 nm	518 nm	FC	RUO
93-0459	Anti-Human CD45 eFluor® 605NC	350 - 590 nm	605 nm	FC	RUO
46-0459	Anti-Human CD45 PerCP-eFluor® 710	488 nm	710 nm	FC	RUO
35-0459	Anti-Human CD45 PE-Cyanine5.5	488 - 567 nm	690 nm	FC	RUO
13-0459	Anti-Human CD45 Biotin			FC	RUO

Related Products

Cat. No.	Name	Excite	Emit	Application	Reg.
15-4714	Mouse IgG1 K Isotype Control PE-Cyanine5	488 - 561 nm		FC	RUO

References

References: Ninomiya M, Abe A, Katsumi A, Xu J, Ito M, Arai F, Suda T, Ito M, Kiyoi H, Kinoshita T, Naoe T. Homing, proliferation and survival sites of human leukemia cells in vivo in immunodeficient mice. Leukemia. 2007 Jan;21(1):136-42.(HI30, IF frozen)

Bouma-ter Steege JC, Baeten CI, Thijssen VL, Satijn SA, Verhoeven IC, Hillen HF, Wagstaff J, Griffioen AW.Angiogenic profile of breast carcinoma determines leukocyte infiltration. Clin Cancer Res. 2004 Nov 1;10(21):7171-8. (HI30, IHC frozen)

Knapp, W., B. Dorken, et al. eds. (1989). Leucocyte Typing IV: White Cell Differentiation Antigens. Oxford University Press. New York.

View More Products

Antigens	Area of Biology	Cell Type	Formats
CD45	Adaptive Immunity Cell Signaling	B Cells Macrophage & Monocyte Cells NK & NKT Cells T Cells	PE-Cyanine5