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Anti-Human CD44var (v3) Purified

Also known as: VFF-327v3 Phagocytic glycoprotein I, Epican

Clone: VFF-327v3

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# BMS144*

Cat. No. Size
BMS144 100 ug
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Description

Description: Specifically recognizes an epitope encoded by exon v3 on the variant portion of human CD44.

Standard CD44 (CD44s) lacks the entire variable region and is found mainly in cells of lymphohematopoietic origin. The multiple isoforms (designated CD44v; v = variant) contain alternatively spliced exons inserted within the extracellular domain. These isoforms are known as CD44v1, CD44v2, CD44v3, CD44v4, CD44v5, CD44v6, CD44v7, CD44v8, CD44v9, CD44v10, CD44v11.

Details
Host Mouse
Isotype lgG1
Reactivity Human
Conjugate Purified
Reported Applications Flow Cytometric Analysis, Immunohistochemical Staining, Immunohistochemical Staining of Formalin-Fixed Paraffin Embedded Tissue Sections, Western Blotting
Documentation
TDS Link Download TDS
Additional Formats
Cat. No. Name Excite Emit Application Reg.
BMS144BT* Anti-Human CD44var (v3) Biotin FC RUO
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References

Citations: Van Hal,Nicole L.W.; van Dongen,Guus A.M.S.; Ten Brink,Corlinda B.M.; Heider,Karl Heinz; Rech-Weichselbraun,Irene; Snow,Gordon B.; Brakenhoff,Ruud H.. Evaluation of Soluble CD44v6 as a Potential Serum Marker for Head and Neck Squamous Cell Carcinoma. Clinical Cancer Research 1999;5:3534-3541. (Link)

Kaya,Grkan; Tran,Christian; Sorg,Olivier; Hotz,Raymonde; Grand,Denise; Carraux,Pierre; Didierjean,Liliane; Stamenkovic,Ivan; Saurat,Jean Hilaire. Hyaluronate Fragments Reverse Skin Atrophy by a CD44-Dependent Mechanism. PLoS Medicine 2006;3:(Link)

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