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Anti-Human CD43 PE

Also known as: Leukosialin, LSN, Sialophorin, SPN

Clone: eBio84-3C1 (84-3C1)

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 12-0439

Cat. No. Size
12-0439-42 100 tests
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Data for Anti-Human CD43 PE.

Staining of normal human peripheral blood cells with Anti-Human CD3 APC (cat. 17-0038) and Mouse...View More

  • Data for Anti-Human CD43 PE.
Description

Description: The monoclonal antibody ebio84-3C1 reacts with CD43, which is also known as leukosialin, galactoglycoprotein and sialophorin. CD43 is a sialomucin which like many mucins can have both adhesive and anti-adhesive functions. Expression of CD43 is found on most leukocytes except resting B lymphocytes. Proteolytic processing upon activation decreases surface expression. CD43 is involved in activation of T cells, B cells, NK cells, and monocytes. The counter-receptor for CD43 is CD169/SIGLEC-1, which is expressed on macrophages.

Details
Host Mouse
Isotype IgG1
Reactivity Human
Conjugate PE
Laser Blue Laser, Green Laser, Yellow-Green Laser
Emit 575 nm
Excite 488 - 561 nm
Reported Applications Flow Cytometric Analysis
Documentation
TDS Link Download TDS
Additional Formats
Cat. No. Name Excite Emit Application Reg.
17-0439 Anti-Human CD43 APC 633 - 647 nm 660 nm FC RUO
14-0439 Anti-Human CD43 Purified FC, WB RUO
11-0439 Anti-Human CD43 FITC 488 nm FC RUO
Related Products
Cat. No. Name Excite Emit Application Reg.
12-0431 Anti-Mouse CD43 PE 488 - 561 nm 575 nm FC RUO
12-4714 Mouse IgG1 K Isotype Control PE 488 - 561 nm 575 nm FC RUO
17-0038 Anti-Human CD3 APC 633 - 647 nm 660 nm FC RUO
References

References: Borche L, Lozano F, Vilella R, Vives J. CD43 monoclonal antibodies recognize the large sialoglycoprotein of human leukocytes. Eur J Immunol. 1987 Oct;17(10):1523-6.

Schlossman, S., L. Bloumsell, et al. eds. 1995. Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press. New York.

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