Anti-Human CD4 PE-Cy5.5

Also known as: Leu-3, T4

Clone: OKT4 (OKT-4)

RUO: For Research Use Only. Not for use in diagnostic procedures.

Attention: To Be Discontinued. Please see replacement format PerCP-Cy5.5 (45-0048).

SKU# 35-0048

Cat. No.	Size
35-0048-41	25 tests
35-0048-42	100 tests

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Description

Description: The OKT4 monoclonal antibody reacts with human CD4, a 59 kDa cell surface glycoprotein expressed by the majority of thymocytes, a subpopulation of mature T cells (T-helper cells) and in low levels on monocytes. CD4 is a receptor for the human immunodeficiency virus (HIV). The OKT4 antibody recognizes a different epitope than the RPA-T4 monoclonal antibody, and these antibodies do not cross-block binding to each other's respective epitopes.

Details

Host	Mouse
Isotype	IgG2b, k
Reactivity	Human
Emit	690 nm
Excite	488 nm
Legal	FOR NON-COMMERCIAL RESEARCH USE ONLY. NOT FOR THERAPEUTIC OR IN VIVO APPLICATIONS. OTHER USE NEEDS LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. UNDER U.S. PATENT FOR NON-COMMERCIAL RESEARCH USE ONLY. NOT FOR THERAPEUTIC OR IN VIVO APPLICATIONS. OTHER USE NEEDS LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. UNDER U.S. PATENT # 5,268,486, 5,569,587 AND 5,627,027 AND FOREIGN EQUIVALENTS AND PENDING APPLICATIONS. THIS MATERIAL IS SUBJECT TO PROPRIETARY RIGHTS OF GE HEALTHCARE BIO-SCIENCES CORP. AND CARNEGIE MELLON UNIVERSITY AND MADE AND SOLD UNDER LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. THIS PRODUCT IS LICENSED FOR SALE ONLY FOR RESEARCH. IT IS NOT LICENSED FOR ANY OTHER USE. THERE IS NO IMPLIED LICENSE HEREUNDER FOR ANY COMMERCIAL USE. COMMERCIAL USE shall include: 1. sale, lease, license or other transfer of the material or any material derived or produced from it; 2. sale, lease, license or other grant of rights to use this Material or any material derived or produced from it; 3. use of this material to perform services for a fee for third parties. IF YOU REQUIRE A COMMERCIAL LICENSE TO USE THIS MATERIAL AND DO NOT HAVE ONE, RETURN THIS MATERIAL, UNOPENED TO EBIOSCIENCE, INC. 10255 SCIENCE CENTER DRIVE, SAN DIEGO, CALIFORNIA 92121 USA AND ANY MONEY PAID FOR THE MATERIAL WILL BE REFUNDED.
Reported Applications	Flow Cytometric Analysis

Documentation

For complete product information, please download the TDS or IFU document.

TDS Link	Download TDS

Additional Formats

Cat. No.	Name	Excite	Emit	Application	Reg.
51-0048	Anti-Human CD4 Alexa Fluor® 647	633 nm	668 nm	FC	RUO
53-0048	Anti-Human CD4 Alexa Fluor® 488	488 nm	519 nm	FC	RUO
17-0048	Anti-Human CD4 APC	633 nm	660 nm	FC	RUO
93-0048	Anti-Human CD4 eFluor® 605NC	350 - 590 nm	605 nm	FC	RUO
16-0048	Anti-Human CD4 Functional Grade Purified			FC, IP	RUO
56-0048	Anti-Human CD4 Alexa Fluor® 700	633 nm	723 nm	FC	RUO
13-0048	Anti-Human CD4 Biotin			FC	RUO
14-0048	Anti-Human CD4 Purified			FC, IP	RUO
48-0048	Anti-Human CD4 eFluor® 450	405 nm	450 nm	FC	RUO
45-0048	Anti-Human CD4 PerCP-Cy5.5	488 nm	690 nm	FC	RUO
12-0048	Anti-Human CD4 PE	488 nm	575 nm	FC	RUO
11-0048	Anti-Human CD4 FITC	488 nm	518 nm	FC	RUO

References

References: Bour S, Boulerice F, Wainberg MA. Inhibition of gp160 and CD4 maturation in U937 cells after both defective and productive infections by human immunodeficiency virus type 1. J Virol. 1991 Dec;65(12):6387-96. (OKT4, IP, PubMed)

Reinherz EL, Kung PC, Goldstein G, Schlossman SF. 1979. Separation of functional subsets of human T cells by a monoclonal antibody. Proc Natl Acad Sci. 76(8): 4061-5.

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Antigens	Area of Biology	Cell Type
CD4	Adaptive Immunity	Macrophage & Monocyte Cells T Cells Th17 Cells Treg Cells