CD36 FITC

Description: The monoclonal antibody NL07 recognizes human CD36, which is a member of the class B scavenger receptor family. CD36 was originally identified as a platelet-membrane glycoprotein also called glycoprotein IV and a receptor for thrombospondin-1 (TSP-1) and extracellular matrix proteins. Binding to TSP-1 is mediated by the CLESH (CD36 LIMP-II Emp sequence homology) domain of CD36. CD36 is expressed on platelets, mature monocytes and macrophages, microvascular endothelial cells and on some macrophage derived dendritic cells.

References: Procedures for the Collection of Diagnostic Blood Specimens by Venipuncture (H3-A6), 3rd Edition published by the National Committee for Clinical Laboratory Standards.

Knapp W, Dorken B, et al, eds. Leucocyte Typing IV: White Cell Differentiation Antigens. Oxford University Press. New York. 1989.

Alessio M, Ghigo D, Garbarino G, Geuna M, Malavasi F. Analysis of the human CD36 leucocyte differentiation antigen by means of the monoclonal antibody NL07. Cell Immunol. 1991. Oct 15;137(2):487-500.