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  • Anti-Human CD326 (EpCAM) Alexa Fluor® 647 (To Be Discontinued. Refer to Replacement Format® eFluor 660, cat. 50-9326)

Anti-Human CD326 (EpCAM) Alexa Fluor® 647 (To Be Discontinued. Refer to Replacement Format® eFluor 660, cat. 50-9326)

Also known as: Ep-CAM, Epithelial cell adhesion molecule, KSA, TROP1

Clone: 1B7

RUO: For Research Use Only. Not for use in diagnostic procedures.

Attention: To Be Discontinued. Refer to replacement format eFluor® 660 Cat. No. 50-9326

SKU# 51-9326

Cat. No. Size
51-9326-71 25 tests
51-9326-73 100 tests
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Data for Anti-Human CD326 (EpCAM) Alexa Fluor® 647 (To Be Discontinued. Refer to NEW Format: eFluor® 660 cat. 50-9326).

Staining of A549 human lung carcinoma cell line with Mouse IgG1 kappa Isotype Control Alexa Fluor®...View More

  • Data for Anti-Human CD326 (EpCAM) Alexa Fluor® 647 (To Be Discontinued. Refer to NEW Format: eFluor® 660 cat. 50-9326).
Description

Description: EpCAM (Epithelial cell adhesion molecule, CD326, KSA, TROP1) is a 40 kD cell-surface adhesion molecule participating in homophilic, calcium-independent cell-cell interactions. EpCAM is a type-I transmembrane protein, and is expressed primarily on the basolateral surface of most epithelia. Although normal epithelia express low levels of EpCAM, increased expression has been correlated with increased proliferation and progression to a mesenchymal phenotype. EpCAM has also been used as a diagnostic marker on circulating metastatic carcinoma cells, while cancer cells of non-epithelial origin do not express EpCAM.

Details
Host Mouse
Isotype IgG1, kappa
Reactivity Human
Conjugate Alexa Fluor 647
Laser Red Laser
Emit 668 nm
Excite 633 nm
Legal Alexa Fluor® and Pacific Blue® are registered trademarks of and licensed under patents assigned to Molecular Probes, Inc. for research use only. This product is subject to an agreement between Molecular Probes, Inc. and eBioscience, and the manufacture, use, sale or import of this product may be subject to one or more U.S. patents, pending applications and corresponding foreign equivalents, owned by Molecular Probes, Inc. (a wholly owned subsidiary of Invitrogen Corp). The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product for life science research or as an ASR. The buyer cannot use this product for manufacturing or for any other screening (specifically including use in combination with microarrays or High Content Screening) or testing purpose, other than as an ASR. For information on purchasing a license to this product for purposes other than life science research or use as an ASR, contact Molecular Probes, Inc.
Reported Applications Flow Cytometric Analysis
Documentation

For complete product information, please download the TDS or IFU document.

TDS Link Download TDS
Additional Formats
Cat. No. Name Excite Emit Application Reg.
13-9326 Anti-Human CD326 (EpCAM) Biotin FC, IHC RUO
14-9326 Anti-Human CD326 (EpCAM) Purified FC, IHC, IP, WB RUO
46-9326 Anti-Human CD326 (EpCAM) PerCP-eFluor® 710 488 nm 710 nm FC RUO
50-9326 Anti-Human CD326 (EpCAM) eFluor® 660 (Alexa Fluor® 647 replacement) 633 nm 668 nm FC RUO
12-9326 Anti-Human CD326 (EpCAM) PE 488 - 561 nm 575 nm FC RUO
References

References: Suzuki K, Nakamura K, Kato K, Hamada H, Tsukamoto T. Exploration of target molecules for prostate cancer gene therapy. Prostate. 2007 Aug 1;67(11):1163-73. (1B7, FC, IHC, PubMed)

Rao CG, Chianese D, Doyle GV, Miller MC, Russell T, Sanders RA Jr, Terstappen LW. Expression of epithelial cell adhesion molecule in carcinoma cells present in blood and primary and metastatic tumors. Int J Oncol. 2005 Jul;27(1):49-57. (PubMed)

Litvinov SV, Bakker HA, Gourevitch MM, Velders MP, Warnaar SO. Evidence for a role of the epithelial glycoprotein 40 (Ep-CAM) in epithelial cell-cell adhesion. Cell Adhes Commun. 1994 Oct;2(5):417-28. (PubMed)

Litvinov SV, Velders MP, Bakker HA, Fleuren GJ, Warnaar SO. Ep-CAM: a human epithelial antigen is a homophilic cell-cell adhesion molecule. J Cell Biol. 1994 Apr;125(2):437-46. (PubMed)

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