Description: CD30, Human CD30 is a member of the tumor necrosis factor (TNF) receptor family 8 CD30 is highly expressed on Hodgkins and Reed-Sternberg cells as well as activated T and B cells. CD30 has been shown to interact with a number of proteins including TRAF1, TRAF2, TRAF3, TRAF5, NPM-ALK, TRAF-interacting protein, and CD30 ligand (CD153). Signaling through CD30 is thought to limit the proliferative potential of autoreactive CD8 effector T cells and protect against autoimmunity.
